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Intensol","Dexamethasonum","Dexamonozon","Dexapos","Dexinoral","Dexone","Dinormon","Fluorodelta","Fortecortin","Gammacorten","Hexadecadrol","Hexadrol","Lokalison-F","Loverine","Methylfluorprednisolone","Millicorten","Mymethasone","Orgadrone","Spersadex","TaperDex","Visumetazone","ZoDex"],"type":"DRUG"},{"name":"Lenalidomide","synonyms":["CC-5013","CC5013","CDC 501","Revlimid"],"type":"DRUG"},{"name":"Quality-of-Life Assessment","synonyms":["Quality of Life Assessment"],"type":"OTHER"}],"nct_id":"NCT04566328","official_title":"Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase 3 Trial for Newly Diagnosed Multiple Myeloma Not Intended for Early Autologous Transplantation","overall_status":"RECRUITING","phase":["PHASE3"],"primary_completion_date":{"date":"2027-12-31","type":"ESTIMATED"},"primary_endpoints":[{"description":"Will be estimated using the Kaplan-Meier (KM) method and compared using a stratified log-rank test. Stratified cox proportional hazards regression will produce treatment hazard ratio (bortezomib, daratumumab and hyaluronidase-fihj (daratumumab), lenalidomide and dexamethasone \\[Btz-DRd\\] then daratumumab, lenalidomide and dexamethasone \\[DRd\\] then daratumumab and lenalidomide \\[DR\\]).","measure":"Consolidation overall survival","timeFrame":"Time from Step 2 randomization at the start of consolidation to death or to the date last known alive, assessed up to 15 years"}],"registry_last_updated":"2026-08-19","registry_url":"https://clinicaltrials.gov/study/NCT04566328","short_name":"EQUATE","short_name_basis":"canonical_name","sponsor":"ECOG-ACRIN Cancer Research Group","start_date":{"date":"2021-02-24","type":"ACTUAL"},"study_design":"interventional, randomized, sequential, phase3","study_ids":[{"id":"EAA181","type":"sponsor_study_id"},{"domain":"CTRP (Clinical Trial Reporting Program)","id":"NCI-2020-06647","type":"registry"},{"id":"U10CA180820","type":"nih"}],"study_type":"INTERVENTIONAL"}}}