{"preliminary_commentary":{"by_channel":{"x_thread":4},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"limited metastatic colorectal cancer","name":"A022101","nct_id":"NCT05673148","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=a022101-nct05673148. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Patients undergo TAT on study, consisting of SABR with or without surgical resection and/or microwave ablation. Patients also receive SOC chemotherapy on study. Patients also undergo CT or MRI or PET/CT scans throughout the trial.","label":"Arm 1 (TAT, SOC chemotherapy","type":"EXPERIMENTAL"},{"description":"Patients receive SOC chemotherapy on study. Patients also undergo Patients also undergo CT or MRI or PET/CT scans throughout the trial.","label":"Arm 2 (SOC chemotherapy)","type":"ACTIVE_COMPARATOR"}],"collaborators":["National Cancer Institute (NCI)"],"completion_date":{"date":"2032-08-12","type":"ESTIMATED"},"conditions":["Metastatic Colorectal Adenocarcinoma","Stage IV Colorectal Cancer AJCC v8","Oligometastatic Colorectal Carcinoma"],"enrollment":{"count":146,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Stereotactic Ablative Radiotherapy","otherNames":["SABER","SABR/SBRT"],"type":"PROCEDURE"},{"name":"Resection","otherNames":["Surgical resection"],"type":"PROCEDURE"},{"name":"Microwave Ablation","otherNames":["Ablation"],"type":"PROCEDURE"},{"name":"Chemotherapy","otherNames":["Chemo"],"type":"DRUG"},{"name":"Computed Tomography","otherNames":["CAT","CAT Scan","Computed Axial Tomography","CT Scan"],"type":"PROCEDURE"},{"name":"Magnetic Resonance Imaging","otherNames":["MRI"],"type":"PROCEDURE"},{"name":"Positron Emission Tomography","otherNames":["Medical Imaging, Positron Emission Tomography","PET","PET Scan"],"type":"PROCEDURE"}],"last_update":"2026-11-03","lead_sponsor":"Alliance for Clinical Trials in Oncology","official_title":"A Pragmatic Randomized Phase II Trial Evaluating Total Ablative Therapy for Patients With Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur)","overall_status":"RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2028-07-03","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Overall Survival (OS)","timeFrame":"From the date of randomization to the date of death due to all causes, assessed up to 5 years"}],"references":[{"citation":"Hitchcock KE, Miller ED, Shi Q, Dixon JG, Gholami S, White SB, Wu C, Goulet CC, George M, Jee KW, Wright CL, Yaeger R, Shergill A, Hong TS, George TJ, O'Reilly EM, Meyerhardt JA, Romesser PB. Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). BMC Cancer. 2024 Feb 13;24(1):201. doi: 10.1186/s12885-024-11899-2.","pmid":"38350888","type":"DERIVED"},{"citation":"Miller ED, Hitchcock KE, Romesser PB. Oligometastatic Colorectal Cancer: A Review of Definitions and Patient Selection for Local Therapies. J Gastrointest Cancer. 2023 Dec;54(4):1116-1127. doi: 10.1007/s12029-022-00900-5. Epub 2023 Jan 18.","pmid":"36652155","type":"DERIVED"}],"start_date":{"date":"2023-10-09","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial","url":"https://clinicaltrials.gov/study/NCT05673148"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/a022101-nct05673148"}