{"preliminary_commentary":{"by_channel":{"podcast":6,"x_thread":4,"youtube":3},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT03914625\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"name":"AALL1731","nct_id":"NCT03914625","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=aall1731-nct03914625. The price is an estimate of verified HCP statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified HCP statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Arm A: See detailed description.","label":"Arm A (SR-Avg control)","type":"ACTIVE_COMPARATOR"},{"description":"Arm B: See detailed description.","label":"Arm B (SR-Avg experimental)","type":"EXPERIMENTAL"},{"description":"Arm C: See detailed description.","label":"Arm C (SR-High Control)","type":"ACTIVE_COMPARATOR"},{"description":"Arm D See detailed description.","label":"Arm D (SR-High experimental)","type":"EXPERIMENTAL"},{"description":"See detailed description.","label":"B-LLy","type":"EXPERIMENTAL"},{"description":"See detailed description.","label":"DS B-ALL","type":"EXPERIMENTAL"},{"description":"See detailed 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risk average (SR-Avg) B-ALL patients based on randomization with addition of blinatumomab","timeFrame":"5.3 years"},{"measure":"DFS in boys in the SR-favorable subset of SR B-ALL with or without Down syndrome (DS)","timeFrame":"5.1 years"}],"references":[{"citation":"Gupta S, Rau RE, Kairalla JA, Rabin KR, Wang C, Angiolillo AL, Alexander S, Carroll AJ, Conway S, Gore L, Kirsch I, Kubaney HR, Li AM, McNeer JL, Militano O, Miller TP, Moyer Y, O'Brien MM, Okada M, Reshmi SC, Shago M, Wagner E, Winick N, Wood BL, Haworth-Wright T, Zaman F, Zugmaier G, Zupanec S, Devidas M, Hunger SP, Teachey DT, Raetz EA, Loh ML. Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children. N Engl J Med. 2025 Feb 27;392(9):875-891. doi: 10.1056/NEJMoa2411680. Epub 2024 Dec 7.","pmid":"39651791","type":"DERIVED"},{"citation":"Sora F, Annunziata M, Laurenti L, Giammarco S, Chiusolo P, Innocenti I, Autore F, Metafuni E, Galli E, Bacigalupo A, Ferrara F, Sica S. Blinatumomab as a successful and safe therapy in Down syndrome patients with relapsed/refractory b-precursor acute lymphoblastic leukaemia: Case reports and literature review. Pediatr Blood Cancer. 2021 Jul;68(7):e29044. doi: 10.1002/pbc.29044. Epub 2021 Apr 12. No abstract available.","pmid":"33844429","type":"DERIVED"}],"start_date":{"date":"2019-07-03","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia","url":"https://clinicaltrials.gov/study/NCT03914625"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/aall1731-nct03914625"}