{"commentary":{"count":28,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":13,"podcast":9,"youtube":6},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT00014612\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"AMAROS","nct_id":"NCT00014612","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=amaros-nct00014612. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 13–40 commentary sources"},"registry":{"acronym":"AMAROS","arms":[{"description":"complete axillary lymph node dissection","label":"axillary lymph node dissection","type":"ACTIVE_COMPARATOR"},{"description":"axillary radiotherapy, daily for 5 days a week, for 5 weeks","label":"axillary radiotherapy","type":"EXPERIMENTAL"}],"collaborators":["ALMANAC Trialists Group","Borstkanker Onderzoeksgroup Nederland"],"completion_date":{"date":"2013-03","type":"ACTUAL"},"conditions":["Breast Cancer"],"enrollment":{"count":4813,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"axillary lymph node dissection","type":"PROCEDURE"},{"name":"lymphoscintigraphy","type":"PROCEDURE"},{"name":"therapeutic conventional surgery","type":"PROCEDURE"},{"name":"radiation therapy","type":"RADIATION"}],"last_update":"2013-10-29","lead_sponsor":"European Organisation for Research and Treatment of Cancer - EORTC","official_title":"After Mapping Of The Axilla: Radiotherapy Or Surgery","overall_status":"COMPLETED","phases":["PHASE3"],"primary_completion_date":{"date":"2010-11","type":"ACTUAL"},"primary_outcomes":[{"measure":"Axillary recurrence rate","timeFrame":"from randomization"}],"references":[{"citation":"Straver ME, Meijnen P, van Tienhoven G, van de Velde CJ, Mansel RE, Bogaerts J, Demonty G, Duez N, Cataliotti L, Klinkenbijl J, Westenberg HA, van der Mijle H, Hurkmans C, Rutgers EJ. Role of axillary clearance after a tumor-positive sentinel node in the administration of adjuvant therapy in early breast cancer. J Clin Oncol. 2010 Feb 10;28(5):731-7. doi: 10.1200/JCO.2008.21.7554. Epub 2009 Dec 28.","pmid":"20038733","type":"RESULT"},{"citation":"Straver ME, Meijnen P, van Tienhoven G, van de Velde CJ, Mansel RE, Bogaerts J, Duez N, Cataliotti L, Klinkenbijl JH, Westenberg HA, van der Mijle H, Snoj M, Hurkmans C, Rutgers EJ. Sentinel node identification rate and nodal involvement in the EORTC 10981-22023 AMAROS trial. Ann Surg Oncol. 2010 Jul;17(7):1854-61. doi: 10.1245/s10434-010-0945-z. Epub 2010 Mar 19.","pmid":"20300966","type":"RESULT"},{"citation":"Straver ME, Meijnen P, van Tienhoven G, et al.: Technical aspects of the sentinel node biopsy in the EORTC AMAROS sentinel node trial. [Abstract] 31st Annual San Antonio Breast Cancer Symposium, December 10-14, 2008, San Antonio, Texas. A-1006, 2008.","pmid":null,"type":"RESULT"},{"citation":"Meijnen P, Rutgers EJT, van de Velde CJH, et al.: EORTC 10981-22023 trial. AMAROS: after mapping of the axilla: radiotherapy or surgery? Trial update. [Abstract] Eur J Cancer 2 (Suppl 3): A-79, 79, 2004.","pmid":null,"type":"RESULT"},{"citation":"Hurkmans CW, Borger JH, Rutgers EJ, van Tienhoven G; EORTC Breast Cancer Cooperative Group; Radiotherapy Cooperative Group. Quality assurance of axillary radiotherapy in the EORTC AMAROS trial 10981/22023: the dummy run. Radiother Oncol. 2003 Sep;68(3):233-40. doi: 10.1016/s0167-8140(03)00194-4.","pmid":"13129630","type":"RESULT"},{"citation":"Donker M, Slaets L, van Tienhoven G, Rutgers EJ. [Axillary lymph node dissection versus axillary radiotherapy in patients with a positive sentinel node: the AMAROS trial]. Ned Tijdschr Geneeskd. 2015;159:A9302. Dutch.","pmid":"26488192","type":"DERIVED"},{"citation":"Donker M, van Tienhoven G, Straver ME, Meijnen P, van de Velde CJ, Mansel RE, Cataliotti L, Westenberg AH, Klinkenbijl JH, Orzalesi L, Bouma WH, van der Mijle HC, Nieuwenhuijzen GA, Veltkamp SC, Slaets L, Duez NJ, de Graaf PW, van Dalen T, Marinelli A, Rijna H, Snoj M, Bundred NJ, Merkus JW, Belkacemi Y, Petignat P, Schinagl DA, Coens C, Messina CG, Bogaerts J, Rutgers EJ. Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial. Lancet Oncol. 2014 Nov;15(12):1303-10. doi: 10.1016/S1470-2045(14)70460-7. Epub 2014 Oct 15.","pmid":"25439688","type":"DERIVED"},{"citation":"Donker M, Straver ME, van Tienhoven G, van de Velde CJ, Mansel RE, Litiere S, Werutsky G, Duez NJ, Orzalesi L, Bouma WH, van der Mijle H, Nieuwenhuijzen GA, Veltkamp SC, Helen Westenberg A, Rutgers EJ. Comparison of the sentinel node procedure between patients with multifocal and unifocal breast cancer in the EORTC 10981-22023 AMAROS Trial: identification rate and nodal outcome. Eur J Cancer. 2013 Jun;49(9):2093-100. doi: 10.1016/j.ejca.2013.02.017. Epub 2013 Mar 19.","pmid":"23522754","type":"DERIVED"}],"start_date":{"date":"2001-02"},"study_type":"INTERVENTIONAL","title":"Comparison of Complete Axillary Lymph Node Dissection With Axillary Radiation Therapy in Treating Women With Invasive Breast Cancer","url":"https://clinicaltrials.gov/study/NCT00014612"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/amaros-nct00014612"}