{"commentary":{"count":44,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":33,"podcast":6,"youtube":5},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT00930033\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"CARMENA","nct_id":"NCT00930033","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=carmena-nct00930033. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 41+ commentary sources"},"registry":{"acronym":"CARMENA","arms":[{"description":"Nephrectomy + sunitinib","label":"A","type":"ACTIVE_COMPARATOR"},{"description":"Sunitinib alone","label":"B","type":"EXPERIMENTAL"}],"collaborators":["Pfizer","URC-CIC Paris Descartes Necker Cochin"],"completion_date":{"date":"2018-10-22","type":"ACTUAL"},"conditions":["Metastatic Renal Cell Carcinoma"],"enrollment":{"count":452,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Nephrectomy","type":"PROCEDURE"},{"name":"Sunitinib alone","type":"OTHER"}],"last_update":"2025-09-05","lead_sponsor":"Assistance Publique - Hôpitaux de Paris","official_title":"Randomized Phase III Trial Evaluating the Importance of Nephrectomy in Patients Presenting With Metastatic Renal Cell Carcinoma Treated With Sunitinib","overall_status":"COMPLETED","phases":["PHASE3"],"primary_completion_date":{"date":"2018-10-22","type":"ACTUAL"},"primary_outcomes":[{"measure":"The primary endpoint is overall survival.","timeFrame":"starting at 4 months"}],"references":[{"citation":"Mejean A, Ravaud A, Thezenas S, Chevreau C, Bensalah K, Geoffrois L, Thiery-Vuillemin A, Cormier L, Lang H, Guy L, Gravis G, Rolland F, Linassier C, Lechevallier E, Oudard S, Laguerre B, Gross-Goupil M, Bernhard JC, Colas S, Albiges L, Lebret T, Treluyer JM, Timsit MO, Escudier B. Sunitinib Alone or After Nephrectomy for Patients with Metastatic Renal Cell Carcinoma: Is There Still a Role for Cytoreductive Nephrectomy? Eur Urol. 2021 Oct;80(4):417-424. doi: 10.1016/j.eururo.2021.06.009. Epub 2021 Jun 27.","pmid":"34187771","type":"RESULT"},{"citation":"Mejean A, Ravaud A, Thezenas S, Colas S, Beauval JB, Bensalah K, Geoffrois L, Thiery-Vuillemin A, Cormier L, Lang H, Guy L, Gravis G, Rolland F, Linassier C, Lechevallier E, Beisland C, Aitchison M, Oudard S, Patard JJ, Theodore C, Chevreau C, Laguerre B, Hubert J, Gross-Goupil M, Bernhard JC, Albiges L, Timsit MO, Lebret T, Escudier B. Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma. N Engl J Med. 2018 Aug 2;379(5):417-427. doi: 10.1056/NEJMoa1803675. Epub 2018 Jun 3.","pmid":"29860937","type":"RESULT"},{"citation":"Leon L, Garcia-Figueiras R, Suarez C, Arjonilla A, Puente J, Vargas B, Mendez Vidal MJ, Sebastia C. Recommendations for the clinical and radiological evaluation of response to treatment in metastatic renal cell cancer. Target Oncol. 2014 Mar;9(1):9-24. doi: 10.1007/s11523-013-0304-7. Epub 2013 Dec 12.","pmid":"24338498","type":"DERIVED"}],"start_date":{"date":"2009-09-09","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Clinical Trial to Assess the Importance of Nephrectomy","url":"https://clinicaltrials.gov/study/NCT00930033"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/carmena-nct00930033"}