{"preliminary_commentary":{"by_channel":{"youtube":20,"podcast":11,"x_thread":9,"bluesky_thread":4},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT04567420\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"name":"DARE","nct_id":"NCT04567420","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=dare-nct04567420. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 301+ verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"DARE","arms":[{"description":"Palbociclib/Fulvestrant Combination","label":"Arm A","type":"EXPERIMENTAL"},{"description":"Adjuvant Therapy","label":"Arm B","type":"ACTIVE_COMPARATOR"}],"collaborators":[],"completion_date":{"date":"2028-12-31","type":"ESTIMATED"},"conditions":["Breast Cancer"],"enrollment":{"count":70,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Palbociclib","otherNames":["IBRANCE"],"type":"DRUG"},{"name":"Fulvestrant","otherNames":["Faslodex"],"type":"DRUG"},{"name":"Adjuvant Therapy","otherNames":["Standard of Care"],"type":"DRUG"}],"last_update":"2026-10-15","lead_sponsor":"Criterium, Inc.","official_title":"A Randomized, Phase II Trial of Circulating Tumor DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)","overall_status":"ACTIVE_NOT_RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2027-12-31","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Surveillance/ctDNA screening Phase","timeFrame":"enrollment"},{"measure":"Therapeutic Phase","timeFrame":"through study completion, an average of 6 years"}],"references":[],"start_date":{"date":"2021-02-09","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)","url":"https://clinicaltrials.gov/study/NCT04567420"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/dare-nct04567420"}