{"commentary":{"count":19,"free_build_floor":8,"listing_floor":3,"by_channel":{"youtube":10,"podcast":7,"x_thread":2},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT07786051\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"DEMETER","nct_id":"NCT07786051","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=demeter-nct07786051. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 13–40 commentary sources"},"registry":{"acronym":"DEMETER","arms":[{"description":"Dose 1 = Dexamethasone 3mg once daily, 1 week on, 3 weeks off schedule","label":"Part 1: Dose 1 Dexamethasone + prior ET","type":"EXPERIMENTAL"},{"description":"Dose 2 = Dexamethasone either 1.5mg or 4mg once daily, 1 week on, 3 weeks off schedule. Depending on the results of Part 1.","label":"Part 2: Dose 2 Dexamethasone + prior ET","type":"EXPERIMENTAL"}],"collaborators":["Oncode Institute"],"completion_date":{"date":"2028-11-01","type":"ESTIMATED"},"conditions":["Breast Cancer"],"enrollment":{"count":80,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Dexamethasone (Oral)","type":"DRUG"}],"last_update":"2026-08-25","lead_sponsor":"The Netherlands Cancer Institute","official_title":"DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response - DEMETER Trial A Phase II Clinical Study to Investigate the Efficacy of Dexamethasone as an Adjunct to Endocrine Therapy in ER+, HER2- Metastatic Breast Cancer.","overall_status":"NOT_YET_RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2028-11-01","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Clinical Benefit Rate, which is defined as the proportion of participants having stable disease, partial response or complete response at the 16th week tumour evaluation.","timeFrame":"At the 16th week tumour evaluation."}],"references":[],"start_date":{"date":"2026-11-01","type":"ESTIMATED"},"study_type":"INTERVENTIONAL","title":"DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial)","url":"https://clinicaltrials.gov/study/NCT07786051"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/demeter-nct07786051"}