{"preliminary_commentary":{"by_channel":{"x_thread":12,"x_video":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT06640166\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"name":"ECLYPse","nct_id":"NCT06640166","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=eclypse-nct06640166. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"ECLYPse","arms":[{"description":"Encorafenib plus cetuximab beyond progression in combination with irinotecan-based doublet chemoterapy (FOLFIRI)","label":"encorafenib+cetuximab+FOLFIRI","type":"EXPERIMENTAL"}],"collaborators":["Pierre Fabre Pharma GmbH"],"completion_date":{"date":"2026-06-30","type":"ESTIMATED"},"conditions":["Colorectal Carcinoma","Colorectal Neoplasms","Colorectal Tumor","Colorectal Adenocarcinoma","Colorectal Cancer (CRC)","Colorectal Cancer","Colon Cancer","Colon Adenocarcinoma","Colon Carcinoma","Colon Neoplasm"],"enrollment":{"count":25,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"encorafenib + cetuximab + FOLFIRI","otherNames":["encorafenib","cetuximab","FOLFIRI"],"type":"DRUG"}],"last_update":"2025-02-12","lead_sponsor":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","official_title":"Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.","overall_status":"RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2025-12-31","type":"ESTIMATED"},"primary_outcomes":[{"measure":"6-month Progression Free Survival rate","timeFrame":"6 months after the enrollment of the last patient."}],"references":[],"start_date":{"date":"2024-06-03","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.","url":"https://clinicaltrials.gov/study/NCT06640166"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/eclypse-nct06640166"}