{"preliminary_commentary":{"by_channel":{"podcast":3,"x_thread":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"advanced non-small cell lung cancer","name":"EF-15","nct_id":"NCT00749346","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=ef-15-nct00749346. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Treatment with concomitant Alimta and NovoTTF-100L","label":"A","type":"EXPERIMENTAL"}],"collaborators":[],"completion_date":{"date":"2011-07","type":"ACTUAL"},"conditions":["Non-small Cell Lung Cancer","NSCLC"],"enrollment":{"count":42,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"NovoTTF-100L","otherNames":["TTFields","Pemetrexed","Alimta","Electric fields"],"type":"DEVICE"}],"last_update":"2011-09-27","lead_sponsor":"NovoCure Ltd.","official_title":"An Open Label Pilot Study of NovoTTF-100L in Combination With Pemetrexed (Alimta®) for Advanced Non-small Cell Lung Cancer","overall_status":"COMPLETED","phases":["PHASE1","PHASE2"],"primary_completion_date":{"date":"2011-07","type":"ACTUAL"},"primary_outcomes":[{"measure":"Device related toxicity","timeFrame":"until 2 months after treatment termination"}],"references":[{"citation":"Kirson ED, Gurvich Z, Schneiderman R, Dekel E, Itzhaki A, Wasserman Y, Schatzberger R, Palti Y. Disruption of cancer cell replication by alternating electric fields. Cancer Res. 2004 May 1;64(9):3288-95. doi: 10.1158/0008-5472.can-04-0083.","pmid":"15126372","type":"BACKGROUND"},{"citation":"Kirson ED, Dbaly V, Tovarys F, Vymazal J, Soustiel JF, Itzhaki A, Mordechovich D, Steinberg-Shapira S, Gurvich Z, Schneiderman R, Wasserman Y, Salzberg M, Ryffel B, Goldsher D, Dekel E, Palti Y. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10152-7. doi: 10.1073/pnas.0702916104. Epub 2007 Jun 5.","pmid":"17551011","type":"BACKGROUND"},{"citation":"Salzberg M, Kirson E, Palti Y, Rochlitz C. A pilot study with very low-intensity, intermediate-frequency electric fields in patients with locally advanced and/or metastatic solid tumors. Onkologie. 2008 Jul;31(7):362-5. doi: 10.1159/000137713. Epub 2008 Jun 24.","pmid":"18596382","type":"BACKGROUND"}],"start_date":{"date":"2008-05"},"study_type":"INTERVENTIONAL","title":"NovoTTF-100L in Combination With Pemetrexed (Alimta®) for Advanced Non-small Cell Lung Cancer","url":"https://clinicaltrials.gov/study/NCT00749346"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/ef-15-nct00749346"}