{"preliminary_commentary":{"by_channel":{"youtube":2,"x_thread":2},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"metastatic prostate cancer","name":"INTERVAL-GAP4","nct_id":"NCT02730338","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=interval-gap4-nct02730338. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"INTERVAL","arms":[{"description":"Supervised high intensity aerobic and resistance exercise tapering to self management with psychosocial support","label":"Arm A: Supervised exercise group","type":"ACTIVE_COMPARATOR"},{"description":"Self directed exercise and psychosocial support group","label":"Arm B: Self directed exercise group","type":"OTHER"}],"collaborators":["University of California, San Francisco","Edith Cowan University","King's College London","Centre hospitalier de l'Université de Montréal (CHUM)"],"completion_date":{"date":"2026-10","type":"ESTIMATED"},"conditions":["Metastatic Prostate Cancer"],"enrollment":{"count":866,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"High intensity aerobic and resistance training","otherNames":[],"type":"BEHAVIORAL"},{"name":"Psychosocial support","otherNames":[],"type":"BEHAVIORAL"}],"last_update":"2024-11-27","lead_sponsor":"Movember Foundation","official_title":"INTense ExeRcise for SurviVAL Among Men with Metastatic Prostate Cancer (INTERVAL - GAP4): a Multicentre, Randomised, Controlled, Phase III Study","overall_status":"UNKNOWN","phases":["NA"],"primary_completion_date":{"date":"2025-10","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Overall Survival","timeFrame":"up to 5 years"}],"references":[{"citation":"Umlauff L, Kenfield SA, Newton RU, Hart NH, Saad F, Courneya KS, Greenwood R, Bloch W; INTERVAL-GAP4 Steering Committee/Coordinating Centres Members/Protocol Development Working Group Members; Schumann M. Meeting Aerobic Physical Activity Guidelines and Associations With Physical Fitness in Men With Metastatic Prostate Cancer: Baseline Results of the Multicentre INTERVAL-GAP4 Trial. Cancer Med. 2024 Dec;13(23):e70261. doi: 10.1002/cam4.70261.","pmid":"39632499","type":"DERIVED"},{"citation":"Kim JS, Taaffe DR, Galvao DA, Clay TD, Redfern AD, Gray ES, Newton RU. Enhancing circulatory myokines and extracellular vesicle uptake with targeted exercise in patients with prostate cancer (the MYEX trial): a single-group crossover study. BMC Cancer. 2024 Jul 1;24(1):784. doi: 10.1186/s12885-024-12530-0.","pmid":"38951803","type":"DERIVED"},{"citation":"Newton RU, Kenfield SA, Hart NH, Chan JM, Courneya KS, Catto J, Finn SP, Greenwood R, Hughes DC, Mucci L, Plymate SR, Praet SFE, Guinan EM, Van Blarigan EL, Casey O, Buzza M, Gledhill S, Zhang L, Galvao DA, Ryan CJ, Saad F. Intense Exercise for Survival among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol. BMJ Open. 2018 May 14;8(5):e022899. doi: 10.1136/bmjopen-2018-022899.","pmid":"29764892","type":"DERIVED"}],"start_date":{"date":"2016-01","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"INTense ExeRcise for SurviVAL Among Men with Metastatic Prostate Cancer (INTERVAL - GAP4)","url":"https://clinicaltrials.gov/study/NCT02730338"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/interval-gap4-nct02730338"}