{"commentary":{"count":40,"free_build_floor":8,"listing_floor":3,"by_channel":{"youtube":16,"podcast":14,"x_thread":10},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT07510685\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"IRIS","nct_id":"NCT07510685","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=iris-nct07510685. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 13–40 commentary sources"},"registry":{"acronym":"IRIS","arms":[{"description":"Participants undergoing endoscopic urologic surgery requiring postoperative bladder irrigation receive bladder irrigation using a closed-system irrigation device designed to allow manual washouts without opening the catheter system.","label":"Closed-System Bladder Irrigation Device","type":"EXPERIMENTAL"},{"description":"Participants undergoing endoscopic urologic surgery requiring postoperative bladder irrigation receive standard bladder irrigation procedures according to routine clinical practice using a three-way Foley catheter and saline solution.","label":"Standard Bladder Irrigation","type":"ACTIVE_COMPARATOR"}],"collaborators":["Azienda Ospedaliero, Universitaria Pisana"],"completion_date":{"date":"2025-12-31","type":"ACTUAL"},"conditions":["Urinary Tract Infection Bacterial","Benign Prostatic Hyperplasia","Bladder Cancer"],"enrollment":{"count":240,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Closed-System Bladder Irrigation Flow Switch Device","type":"DEVICE"},{"name":"Standard Bladder Irrigation","type":"PROCEDURE"}],"last_update":"2026-04-03","lead_sponsor":"University of Pisa","official_title":"Closed-System Bladder Irrigation for the Reduction of Urinary Tract Infections After Endoscopic Urologic Surgery With Continuous Bladder Irrigation: A Randomized Controlled Trial (IRIS Study)","overall_status":"COMPLETED","phases":["NA"],"primary_completion_date":{"date":"2025-12-31","type":"ACTUAL"},"primary_outcomes":[{"measure":"Incidence of bacteriuria","timeFrame":"Daily from 48 to 72 hours after surgery (three consecutive postoperative days)"}],"references":[{"citation":"Gould CV, Umscheid CA, Agarwal RK, Kuntz G, Pegues DA; Healthcare Infection Control Practices Advisory Committee. Guideline for prevention of catheter-associated urinary tract infections 2009. Infect Control Hosp Epidemiol. 2010 Apr;31(4):319-26. doi: 10.1086/651091. No abstract available.","pmid":"20156062","type":"BACKGROUND"},{"citation":"Yoon HY, Yang HM, Kim CH, Goo YT, Kang MJ, Lee S, Choi YW. Current status of the development of intravesical drug delivery systems for the treatment of bladder cancer. Expert Opin Drug Deliv. 2020 Nov;17(11):1555-1572. doi: 10.1080/17425247.2020.1810016. Epub 2020 Sep 4.","pmid":"32791923","type":"RESULT"},{"citation":"Hagen S, Sinclair L, Cross S. Washout policies in long-term indwelling urinary catheterisation in adults. Cochrane Database Syst Rev. 2010 Mar 17;(3):CD004012. doi: 10.1002/14651858.CD004012.pub4.","pmid":"20238325","type":"RESULT"},{"citation":"Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA Guideline PART II-Surgical Evaluation and Treatment. Erratum. J Urol. 2022 Mar;207(3):743. doi: 10.1097/JU.0000000000002388. Epub 2022 Mar 1. No abstract available.","pmid":"35135337","type":"RESULT"},{"citation":"Kolawole OM, Lau WM, Mostafid H, Khutoryanskiy VV. Advances in intravesical drug delivery systems to treat bladder cancer. Int J Pharm. 2017 Oct 30;532(1):105-117. doi: 10.1016/j.ijpharm.2017.08.120. Epub 2017 Sep 1.","pmid":"28867449","type":"RESULT"},{"citation":"Shepherd AJ, Mackay WG, Hagen S. Washout policies in long-term indwelling urinary catheterisation in adults. Cochrane Database Syst Rev. 2017 Mar 6;3(3):CD004012. doi: 10.1002/14651858.CD004012.pub5.","pmid":"28262925","type":"RESULT"},{"citation":"Getliffe KA. Bladder instillations and bladder washouts in the management of catheterized patients. J Adv Nurs. 1996 Mar;23(3):548-54. doi: 10.1111/j.1365-2648.1996.tb00018.x.","pmid":"8655831","type":"RESULT"},{"citation":"GBD 2019 Benign Prostatic Hyperplasia Collaborators. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Healthy Longev. 2022 Nov;3(11):e754-e776. doi: 10.1016/S2666-7568(22)00213-6. Epub 2022 Oct 20.","pmid":"36273485","type":"RESULT"},{"citation":"Freier, H., Gerhards, L. M., Sondern, D., Schwenke, S., & Thielsch, M. (2022). Usability and User Experience of Medical Devices - Insights from Laypersons and Healthcare Professionals Proceedings of Mensch und Computer 2022, Darmstadt, Germany. https://doi.org/10.1145/3543758.3547534","pmid":null,"type":"RESULT"},{"citation":"Kranz J, Bartoletti R, Bruyere F, Cai T, Geerlings S, Koves B, Schubert S, Pilatz A, Veeratterapillay R, Wagenlehner FME, Bausch K, Devlies W, Horvath J, Leitner L, Mantica G, Mezei T, Smith EJ, Bonkat G. European Association of Urology Guidelines on Urological Infections: Summary of the 2024 Guidelines. Eur Urol. 2024 Jul;86(1):27-41. doi: 10.1016/j.eururo.2024.03.035. Epub 2024 May 6.","pmid":"38714379","type":"RESULT"},{"citation":"Atkins L, Sallis A, Chadborn T, Shaw K, Schneider A, Hopkins S, Bunten A, Michie S, Lorencatto F. Reducing catheter-associated urinary tract infections: a systematic review of barriers and facilitators and strategic behavioural analysis of interventions. Implement Sci. 2020 Jul 6;15(1):44. doi: 10.1186/s13012-020-01001-2.","pmid":"32624002","type":"RESULT"}],"start_date":{"date":"2025-02-01","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Closed-System Bladder Irrigation to Reduce Urinary Tract Infections After Endoscopic Urologic Surgery (IRIS Trial)","url":"https://clinicaltrials.gov/study/NCT07510685"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/iris-nct07510685"}