{"preliminary_commentary":{"by_channel":{"x_thread":16},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT05427383\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":null,"name":"KC-WISE","nct_id":"NCT05427383","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=kc-wise-nct05427383. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"IV KN026 at 30 mg/kg on D1 and IV Paclitaxel at 175 mg/m² on D1 or IV Docetaxel at 75 mg/m² on D1 or IV Irinotecan at 125 mg/m² on D1, D8, Q3W","label":"KN026 + Paclitaxel/ Docetaxel/ Irinotecan","type":"EXPERIMENTAL"},{"description":"IV Placebo at 30 mg/kg on D1 and IV Paclitaxel at 175 mg/m² on D1 or IV Docetaxel at 75 mg/m² on D1 or IV Irinotecan at 125 mg/m² on D1, D8, Q3W","label":"Placebo + Paclitaxel/ Docetaxel/ Irinotecan","type":"EXPERIMENTAL"}],"collaborators":[],"completion_date":{"date":"2026-11","type":"ESTIMATED"},"conditions":["Stomach Cancer"],"enrollment":{"count":286,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"KN026/Placbo Injection","otherNames":[],"type":"DRUG"},{"name":"Paclitaxel Injection","otherNames":[],"type":"DRUG"},{"name":"Docetaxel Injection","otherNames":[],"type":"DRUG"},{"name":"Irinotecan Injection","otherNames":[],"type":"DRUG"}],"last_update":"2023-12-19","lead_sponsor":"Shanghai JMT-Bio Inc.","official_title":"A Randomized, Multicenter, Phase Ⅱ/Ш Clinical Study to Evaluate the Efficacy of KN026 in Combination With Chemotherapy in Subjects With HER2 Positive Advanced Unresectable or Metastatic Gastric Cancer (Including Gastro-esophageal Junction Adenocarcinoma) Who Have Failed First-line Therapy.","overall_status":"RECRUITING","phases":["PHASE2","PHASE3"],"primary_completion_date":{"date":"2025-11","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Progression Free Survival (PFS) according to RECIST 1.1 by IRC","timeFrame":"Up to 2.5 years"},{"measure":"Overall Survival (OS) according to RECIST 1.1 by IRC","timeFrame":"Up to 2.5 years"}],"references":[],"start_date":{"date":"2022-04-07","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy","url":"https://clinicaltrials.gov/study/NCT05427383"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/kc-wise-nct05427383"}