{"preliminary_commentary":{"by_channel":{"x_thread":2,"youtube":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":null,"indication":"epithelial ovarian cancer","name":"KOV-HIPEC-01","nct_id":"NCT01091636","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=kov-hipec-01-nct01091636. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients with Ovarian Cancer after primary cytoreductive surgery or interval cytoreductive surgery","label":"HIPEC","type":"EXPERIMENTAL"},{"description":"Primary cytoreductive surgery or interval cytoreductive surgery","label":"No HIPEC","type":"NO_INTERVENTION"}],"collaborators":["Ajou University"],"completion_date":{"date":"2020-01-10","type":"ACTUAL"},"conditions":["Epithelial Ovarian Cancer"],"enrollment":{"count":184,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Hyperthermic Intraperitoneal Chemotherapy","otherNames":["Belmont Instrument Corporation"],"type":"PROCEDURE"}],"last_update":"2020-02-17","lead_sponsor":"National Cancer Center, Korea","official_title":"Randomized Trial of Intraoperative Hyperthermic Intraperitoneal Chemotherapy Followed by Intravenous Chemotherapy in Patients With Ovarian Cancer","overall_status":"COMPLETED","phases":["PHASE2","PHASE3"],"primary_completion_date":{"date":"2020-01-10","type":"ACTUAL"},"primary_outcomes":[{"measure":"Progression free survival","timeFrame":"2 years"}],"references":[{"citation":"Lim MC, Kang S, Choi J, Song YJ, Park S, Seo SS, Park SY. Hyperthermic intraperitoneal chemotherapy after extensive cytoreductive surgery in patients with primary advanced epithelial ovarian cancer: interim analysis of a phase II study. Ann Surg Oncol. 2009 Apr;16(4):993-1000. doi: 10.1245/s10434-008-0299-y. Epub 2009 Jan 24.","pmid":"19169758","type":"RESULT"},{"citation":"Kim JH, Chun SY, Lee DE, Woo YH, Chang SJ, Park SY, Chang YJ, Lim MC. Cost-effectiveness of hyperthermic intraperitoneal chemotherapy following interval cytoreductive surgery for stage III-IV ovarian cancer from a randomized controlled phase III trial in Korea (KOV-HIPEC-01). Gynecol Oncol. 2023 Mar;170:19-24. doi: 10.1016/j.ygyno.2022.12.021. Epub 2023 Jan 4.","pmid":"36608383","type":"DERIVED"},{"citation":"Kim JH, Lee DE, Lee Y, Ha HI, Chang YJ, Chang SJ, Park SY, Lim MC. Quality of life outcomes from the randomized trial of hyperthermic intraperitoneal chemotherapy following cytoreductive surgery for primary ovarian cancer (KOV-HIPEC-01). J Gynecol Oncol. 2022 Jul;33(4):e54. doi: 10.3802/jgo.2022.33.e54. Epub 2022 May 31.","pmid":"35712968","type":"DERIVED"},{"citation":"Lim MC, Chang SJ, Park B, Yoo HJ, Yoo CW, Nam BH, Park SY; HIPEC for Ovarian Cancer Collaborators. Survival After Hyperthermic Intraperitoneal Chemotherapy and Primary or Interval Cytoreductive Surgery in Ovarian Cancer: A Randomized Clinical Trial. JAMA Surg. 2022 May 1;157(5):374-383. doi: 10.1001/jamasurg.2022.0143.","pmid":"35262624","type":"DERIVED"}],"start_date":{"date":"2010-03"},"study_type":"INTERVENTIONAL","title":"Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Ovarian Cancer","url":"https://clinicaltrials.gov/study/NCT01091636"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/kov-hipec-01-nct01091636"}