{"commentary":{"count":7,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":7},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":false},"name":"LAVA-CRLM","nct_id":"NCT03654131","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=lava-crlm-nct03654131. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":750,"size":"focused","size_rule":"Focused: 1–12 commentary sources"},"registry":{"acronym":"LAVA-CRLM","arms":[{"description":"Percutaneous ultrasound-guided MWA or open surgery MWA. The patient is fully anesthetized during the treatment.","label":"MWA","type":"ACTIVE_COMPARATOR"},{"description":"3 fractions of 15 Gy (in total 45 Gy), 3 fractions per week. The dose is prescribed to the PTV encompassing 67% isodose. The SBRT plan is normalized such that the mean dose to the GTV is 100% = 67.5 Gy.","label":"SBRT","type":"ACTIVE_COMPARATOR"}],"collaborators":[],"completion_date":{"date":"2029-12-03","type":"ESTIMATED"},"conditions":["Colorectal Carcinoma","Liver Metastases"],"enrollment":{"count":100,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"MWA","type":"DEVICE"},{"name":"SBRT","type":"RADIATION"}],"last_update":"2026-03-19","lead_sponsor":"Copenhagen University Hospital, Rigshospitalet","official_title":"Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver - a Randomized Phase II Trail","overall_status":"ACTIVE_NOT_RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2026-01-01","type":"ACTUAL"},"primary_outcomes":[{"measure":"Freedom from local lesion progression (analyzed on patient-level)","timeFrame":"1 year"}],"references":[{"citation":"Risumlund SL, Stick LB, Appelt A, Vogelius IR, Nyhuus B, Schultz NA, Penninga L, van Overeem Felter M, Josipovic M, Larsen PN. Microwave ablation versus stereotactic body radiotherapy for oligometastatic colorectal liver metastases (LAVA-CRLM): a prospective, randomised, phase II trial. Lancet Reg Health Eur. 2026 Sep 25;71:101879. doi: 10.1016/j.lanepe.2026.101879. eCollection 2026 Dec.","pmid":"42829779","type":"DERIVED"}],"start_date":{"date":"2018-07-25","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Microwave Ablation Versus Stereotactic Body Radiotherapy for Colorectal Liver Metastases in Oligometastatic Disease: a Prospective, Randomised, Phase 2 Trial","url":"https://clinicaltrials.gov/study/NCT03654131"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/lava-crlm-nct03654131"}