# LU002 (NCT03137771)

> Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

No report yet. It can be ordered.

## Registry

- Registry record: https://clinicaltrials.gov/study/NCT03137771
- Phase: PHASE2
- Status: ACTIVE_NOT_RECRUITING
- Sponsor: NRG Oncology
- Conditions: Recurrent Non-Small Cell Lung Carcinoma; Stage IV Non-Small Cell Lung Cancer
- Interventions: 3-Dimensional Conformal Radiation Therapy (3D-CRT); Docetaxel; Gemcitabine; Intensity-Modulated Radiation Therapy (IMRT); Pemetrexed Disodium; Stereotactic Body Radiation Therapy (SBRT); Erlotinib Hydrochloride; Pembrolizumab
- Enrollment: 218
- Primary outcome: [Phase II] Progression-free Survival
- Primary outcome: [Phase III] Overall Survival

## Questions raised in the commentary

_Automated, Oct 29, 2026. Not an Erudio report: no source links. Not medical advice._

The commentary discusses NRG-LU002’s evaluation of local consolidative therapy, including radiation or surgery, alongside maintenance systemic therapy for oligometastatic NSCLC, compared with maintenance therapy alone. Discussion covers the trial population and its heterogeneity, definitions and biology of oligometastatic disease, and how patterns of spread may affect interpretation. Speakers raise questions about whether radiation to local nodes influences immunotherapy response, how the role of local therapy may change as systemic treatments improve, and which patients may be appropriate for treatment. Translational ctDNA analyses are discussed.

## Indexed commentary on LU002 so far

Podcasts, YouTube videos and X posts we have indexed that name the trial. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.

- X threads: 106
- YouTube: 22
- Podcasts: 10
- Bluesky threads: 1

## Order

Deep, $1,950, price fixed at order: https://www.erudio.com/contact?report=lu002-nct03137771

## Free preview

POST https://www.erudio.com/api/trial-requests with {"nct_id": "NCT03137771", "email": "<work email>"}; the inbox owner confirms by the emailed link.