{"preliminary_commentary":{"by_channel":{"x_thread":3},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":null,"indication":null,"name":"NAPOLI-2","nct_id":"NCT04005339","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=napoli-2-nct04005339. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Nanoliposomal irinotecan 70 mg/ IV over 90 minutes, every 14 days. Leucovorin 400 mg/ IV over 30 minutes, every 14 days. Fluorouracil 2,400 mg/m IV over 46 hours.","label":"Single Arm","type":"EXPERIMENTAL"}],"collaborators":["Ipsen"],"completion_date":{"date":"2026-12-31","type":"ESTIMATED"},"conditions":["Advanced Biliary Tract Cancer"],"enrollment":{"count":48,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"Nanoliposomal Irinotecan","otherNames":[],"type":"DRUG"},{"name":"Leucovorin","otherNames":[],"type":"DRUG"},{"name":"Fluorouracil","otherNames":[],"type":"DRUG"}],"last_update":"2026-10-27","lead_sponsor":"Georgetown University","official_title":"NAPOLI-2: Phase II Study of Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Previously Treated Advanced Biliary Tract Cancer","overall_status":"ACTIVE_NOT_RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2025-09-03","type":"ACTUAL"},"primary_outcomes":[{"measure":"The Efficacy of Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Advanced Biliary Tract Cancers Following Progression on or Intolerance of Gemcitabine and Platinum Chemotherapy.","timeFrame":"4 months"}],"references":[],"start_date":{"date":"2019-07-29","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer","url":"https://clinicaltrials.gov/study/NCT04005339"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/napoli-2-nct04005339"}