{"preliminary_commentary":{"by_channel":{"x_thread":4,"podcast":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":false},"name":"NCT01597778","nct_id":"NCT01597778","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct01597778. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Participants will receive haploidentical bone marrow transplant using a reduced intensity conditioning regimen.","label":"Haploidentical Bone Marrow Transplant","type":"EXPERIMENTAL"},{"description":"Participants will receive a double umbilical cord blood transplant using a reduced intensity conditioning regimen.","label":"Double Umbilical Cord Blood Transplant","type":"EXPERIMENTAL"}],"collaborators":["National Heart, Lung, and Blood Institute (NHLBI)","National Cancer Institute (NCI)","Blood and Marrow Transplant Clinical Trials Network","National Marrow Donor Program"],"completion_date":{"date":"2020-09-11","type":"ACTUAL"},"conditions":["Acute Lymphocytic Leukemia","Acute Myelogenous Leukemia","Burkitt's Lymphoma","Follicular Lymphoma","Hodgkin Lymphoma","Mantle Cell Lymphoma","Non-Hodgkin Lymphoma"],"enrollment":{"count":368,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"Haploidentical Bone Marrow Transplant","otherNames":[],"type":"BIOLOGICAL"},{"name":"Double Umbilical Cord Blood Transplant","otherNames":[],"type":"BIOLOGICAL"}],"last_update":"2021-12-01","lead_sponsor":"Medical College of Wisconsin","official_title":"A Multi-Center, Phase III, Randomized Trial of RIC and Transplantation of (dUCB) Versus HLA-Haplo Related Bone Marrow for Patients With Hematologic Malignancies.(BMT CTN #1101)","overall_status":"COMPLETED","phases":["PHASE3"],"primary_completion_date":{"date":"2020-09-11","type":"ACTUAL"},"primary_outcomes":[{"measure":"Percentage of Participants With Progression Free Survival (PFS)","timeFrame":"Year 2"}],"references":[{"citation":"Eapen M, O'Donnell P, Brunstein CG, Wu J, Barowski K, Mendizabal A, Fuchs EJ. Mismatched related and unrelated donors for allogeneic hematopoietic cell transplantation for adults with hematologic malignancies. Biol Blood Marrow Transplant. 2014 Oct;20(10):1485-92. doi: 10.1016/j.bbmt.2014.05.015. Epub 2014 May 23.","pmid":"24862638","type":"BACKGROUND"},{"citation":"Roth JA, Bensink ME, O'Donnell PV, Fuchs EJ, Eapen M, Ramsey SD. Design of a cost-effectiveness analysis alongside a randomized trial of transplantation using umbilical cord blood versus HLA-haploidentical related bone marrow in advanced hematologic cancer. J Comp Eff Res. 2014 Mar;3(2):135-44. doi: 10.2217/cer.13.95.","pmid":"24645687","type":"BACKGROUND"},{"citation":"Zhang P, Logan B, Martens MJ. Covariate-Adjusted Group Sequential Comparisons of Survival Probabilities. Stat Med. 2025 Dec;44(28-30):e70339. doi: 10.1002/sim.70339.","pmid":"41350757","type":"DERIVED"},{"citation":"Khanal M, Logan BR, Banerjee A, Fang X, Ahn KW. A Commensurate Prior Model With Random Effects for Survival and Competing Risk Outcomes to Accommodate Historical Controls. Pharm Stat. 2025 Jan-Feb;24(1):e2464. doi: 10.1002/pst.2464.","pmid":"39846144","type":"DERIVED"},{"citation":"Ramsey SD, Bansal A, Li L, O'Donnell PV, Fuchs EJ, Brunstein CG, Eapen M, Thao V, Roth JA, Steuten LMG. Cost-Effectiveness of Unrelated Umbilical Cord Blood Transplantation versus HLA-Haploidentical Related Bone Marrow Transplantation: Evidence from BMT CTN 1101. Transplant Cell Ther. 2023 Jul;29(7):464.e1-464.e8. doi: 10.1016/j.jtct.2023.04.017. Epub 2023 Apr 27.","pmid":"37120135","type":"DERIVED"},{"citation":"El Jurdi N, Martens MJ, Brunstein CG, O'Donnell P, Lee SJ, D'Souza A, Logan B, Hong S, Singh AK, Sandhu K, Shapiro RM, Horowitz MM, Hamilton BK. Health-Related Quality of Life in Double Umbilical Cord Blood versus Haploidentical Marrow Transplantation: A Quality of Life Analysis Report of BMT CTN 1101. Transplant Cell Ther. 2023 Jul;29(7):467.e1-467.e5. doi: 10.1016/j.jtct.2023.04.009. Epub 2023 Apr 22.","pmid":"37088401","type":"DERIVED"},{"citation":"Brunstein CG, DeFor TE, Fuchs EJ, Karanes C, McGuirk JP, Rezvani AR, Eapen M, O'Donnell PV, Weisdorf DJ; Blood and Marrow Transplant Clinical Trials Network. Engraftment of Double Cord Blood Transplantation after Nonmyeloablative Conditioning with Escalated Total Body Irradiation Dosing to Facilitate Engraftment in Immunocompetent Patients. Transplant Cell Ther. 2021 Oct;27(10):879.e1-879.e3. doi: 10.1016/j.jtct.2021.07.006. Epub 2021 Jul 15.","pmid":"34273598","type":"DERIVED"},{"citation":"Fuchs EJ, O'Donnell PV, Eapen M, Logan B, Antin JH, Dawson P, Devine S, Horowitz MM, Horwitz ME, Karanes C, Leifer E, Magenau JM, McGuirk JP, Morris LE, Rezvani AR, Jones RJ, Brunstein CG. Double unrelated umbilical cord blood vs HLA-haploidentical bone marrow transplantation: the BMT CTN 1101 trial. Blood. 2021 Jan 21;137(3):420-428. doi: 10.1182/blood.2020007535.","pmid":"33475736","type":"DERIVED"}],"start_date":{"date":"2012-06","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Double Cord Versus Haploidentical (BMT CTN 1101)","url":"https://clinicaltrials.gov/study/NCT01597778"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct01597778"}