{"commentary":{"count":3,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":3},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":false},"name":"NCT02273375","nct_id":"NCT02273375","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct02273375. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":750,"size":"focused","size_rule":"Focused: 1–12 commentary sources"},"registry":{"acronym":null,"arms":[{"description":"MEDI4736 by intravenous infusion. Treatment from Day 1 for a maximum of 12 months or study drug withdrawal if this occurs earlier.","label":"MEDI4736","type":"EXPERIMENTAL"},{"description":"PLACEBO by intravenous infusion. Treatment from Day 1 for a maximum of 12 months or study drug withdrawal if this occurs earlier","label":"Placebo","type":"PLACEBO_COMPARATOR"}],"collaborators":["Intergroupe Francophone de Cancerologie Thoracique","Thoracic Oncology Group of Australasia (TOGA)","National Health and Medical Research Council, Australia","National Cancer Institute, Naples","Central and Eastern European Oncology Group","Dutch Society of Physicians for Pulmonology and Tuberculosis","Korean Cancer Study Group","Fundación GECP","West Japan Oncology Group","Chinese Thoracic Oncology Group"],"completion_date":{"date":"2026-09-01","type":"ACTUAL"},"conditions":["Non-Small Cell Lung Cancer"],"enrollment":{"count":1415,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"MEDI4736","type":"DRUG"},{"name":"Placebo","type":"DRUG"}],"last_update":"2026-09-14","lead_sponsor":"Canadian Cancer Trials Group","official_title":"A Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 In Completely Resected Non-Small Cell Lung Cancer","overall_status":"COMPLETED","phases":["PHASE3"],"primary_completion_date":{"date":"2025-07-23","type":"ACTUAL"},"primary_outcomes":[{"measure":"Compare Disease Free Survival (DFS) for Patients With NSCLC That is PD-L1 Expression TC ≥ 25% and Patients Without EGFR Exon 21 L858R Mutation or Exon 19 Deletions or ALK Gene Rearrangements","timeFrame":"Up to 8.3 years"}],"references":[{"citation":"Glenwood D. Goss, MD, FCP(SA), FRCPC 1; Gail E. Darling, MD, FRCS 2 ; Virginie Westeel, MD 3; Kazuhiko Nakagawa, MD, PhD 4; Bartomeu Massut´ı, MD 5 ; Francesco Perrone, MD 6 ; Sue-Anne McLachlan, MBBS, FRACP 7 ; Jin Hyoung Kang, MD 8 ; Yi-Long Wu, MD 9; Anne-Marie C. Dingemans, MD, PhD 10 ; Rafal Dziadziuszko, MD, PhD 11 ; Laurent Greillier, MD, PhD 12 ; Morihito Okada, MD 13 ; Clarisse Audigier-Valette, MD 14 ; Shunichi Sugawara, MD 15 ; Ernest Nadal, MD, PhD 16 ; Annamaria Catino, MD 17;Anne-Claire Toffart, MD, PhD 18 ; Tetsuya Mitsudomi, MD, PhD 19; Renaud Whittom, MD, FRCPC 20 ; Manuel Domine, MD 21; Nobuyuki Yamamoto, MD 22 ; Olivier Molinier, MD 23 ; Franck Morin, MSc 24 ; Penelope A. Bradbury, MD 25 ; Martin R. Stockler, MBBS, FRACP 26 ; Keyue Ding, PhD 27 ; and Christopher J. O'Callaghan, PhD, DVM 27","pmid":null,"type":"RESULT"},{"citation":"Goss GD, Darling GE, Westeel V, Nakagawa K, Massuti B, Perrone F, McLachlan SA, Kang JH, Wu YL, Dingemans AC, Dziadziuszko R, Greillier L, Okada M, Audigier-Valette C, Sugawara S, Nadal E, Catino A, Toffart AC, Mitsudomi T, Whittom R, Domine M, Yamamoto N, Molinier O, Morin F, Bradbury PA, Stockler MR, Ding K, O'Callaghan CJ. Adjuvant Durvalumab in Completely Resected Early-Stage Non-Small Cell Lung Cancer. J Clin Oncol. 2026 Mar;44(7):553-564. doi: 10.1200/JCO-25-01828. Epub 2026 Jan 13.","pmid":"41529222","type":"DERIVED"}],"start_date":{"date":"2015-02-24","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC","url":"https://clinicaltrials.gov/study/NCT02273375"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct02273375"}