{"preliminary_commentary":{"by_channel":{"x_thread":27,"podcast":4,"youtube":2},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT02537548\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":{"generated_at":"2026-11-02T18:46:52.819Z","note":"Automated from all 33 indexed sources (Nov 2018 – Sep 2026). Each question is raised in at least two. Not an Erudio report: no source links. Not medical advice.","passages_read":38,"text":"- Whether results apply beyond highly selected, low-volume disease\n- Whether longer follow-up changes estimates of recurrence risk\n- How RPLND compares with chemotherapy or radiotherapy\n\nAlso discussed: PET for nodal assessment, salvage treatment after relapse, long-term treatment toxicity."},"drugs_tested":[],"indication":"testicular seminoma with limited retroperitoneal lymphadenopathy","name":"NCT02537548","nct_id":"NCT02537548","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct02537548. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 301+ verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Patients undergo RPLND.","label":"Treatment (RPLND)","type":"EXPERIMENTAL"}],"collaborators":["National Cancer Institute (NCI)"],"completion_date":{"date":"2027-12-31","type":"ESTIMATED"},"conditions":["Lymphadenopathy","Stage I Testicular Seminoma","Stage II Testicular Seminoma"],"enrollment":{"count":55,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Laboratory Biomarker Analysis","otherNames":[],"type":"OTHER"},{"name":"Retroperitoneal Lymph Node Dissection","otherNames":["RPLND"],"type":"PROCEDURE"}],"last_update":"2026-06-09","lead_sponsor":"University of Southern California","official_title":"Surgery in Early Metastatic Seminoma (SEMS): Phase II Trial of Retroperitoneal Lymph Node Dissection as First-Line Treatment for Testicular Seminoma With Isolated Retroperitoneal Disease (1-3cm)","overall_status":"ACTIVE_NOT_RECRUITING","phases":["NA"],"primary_completion_date":{"date":"2026-12-31","type":"ESTIMATED"},"primary_outcomes":[{"measure":"RFS","timeFrame":"From RPLND to the time of recurrence or death, whichever comes first., assessed at 2 years after RPLND"}],"references":[{"citation":"Hu B, Alsyouf M, Farkouh A, Cary C, Masterson T, Einhorn L, Adra N, Boorjian SA, Kollmannsberger C, Schuckman A, So A, Black PC, Bagrodia A, Skinner E, Alemozaffar M, Brand T, Eggener S, Pierorazio P, Stratton K, Nappi L, Nichols C, Daneshmand S. Accuracy of 18F-Fluorodeoxyglucose Positron Emission Tomography in Early Metastatic Testicular Seminoma: Analysis From the SEMS Trial. J Urol. 2025 Sep;214(3):272-279. doi: 10.1097/JU.0000000000004561. Epub 2025 Apr 9.","pmid":"40203124","type":"DERIVED"},{"citation":"Daneshmand S, Cary C, Masterson T, Einhorn L, Adra N, Boorjian SA, Kollmannsberger C, Schuckman A, So A, Black P, Bagrodia A, Skinner E, Alemozaffar M, Brand T, Eggener S, Pierorazio P, Stratton K, Nappi L, Nichols C, Luo C, Li M, Hu B. Surgery in Early Metastatic Seminoma: A Phase II Trial of Retroperitoneal Lymph Node Dissection for Testicular Seminoma With Limited Retroperitoneal Lymphadenopathy. J Clin Oncol. 2023 Jun 1;41(16):3009-3018. doi: 10.1200/JCO.22.00624. Epub 2023 Mar 13.","pmid":"36913642","type":"DERIVED"}],"start_date":{"date":"2015-08-28","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma","url":"https://clinicaltrials.gov/study/NCT02537548"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.1","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct02537548"}