{"preliminary_commentary":{"by_channel":{"x_thread":18,"youtube":10,"podcast":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT02750826\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":null,"name":"BWEL","nct_id":"NCT02750826","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=bwel-nct02750826. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 301+ verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Patients will receive a standardized intervention focusing on healthy living. This will include mailings at study entry and one year later describing healthy lifestyle behaviors. All participants will also receive a 2-year subscription to a health magazine. In addition, all study participants will be invited to join twice-yearly Webinars/teleconferences that focus on breast cancer and other health topics, such as treatment updates in breast cancer, management of menopausal side effects, general cancer screening, etc. Finally, the study will also provide birthday and holiday greeting cards and a twice-yearly study newsletter with study updates and other general breast cancer news.","label":"Arm 1: Health Education Program","type":"OTHER"},{"description":"Patients will receive a standardized intervention focusing on healthy living as described in the Arm 1 (Health Education Program). In addition, patients will utilize a standardized, 2-year, telephone-based weight loss intervention. The intervention will include individual weight loss, caloric restriction, and physical activity goals for each participant. It will be administered through semi-structured phone calls delivered by trained coaches at the BWEL call center and supplemented through print and on-line materials. The intervention will utilize a toolbox approach that will allow for tailoring for the individual participant.","label":"Arm 2: Health Education Program + Weight Loss Intervention","type":"OTHER"}],"collaborators":["National Cancer Institute (NCI)","Division of Cancer Control","NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)","Canadian Cancer Trials Group"],"completion_date":{"date":"2030-05-30","type":"ESTIMATED"},"conditions":["Breast Ductal Carcinoma In Situ","Invasive Breast Carcinoma","Stage II Breast Cancer AJCC v6 and v7","Stage IIB Breast Cancer AJCC v6 and v7","Stage IIIA Breast Cancer AJCC v7","Stage IIIC Breast Cancer AJCC v7","Synchronous Bilateral Breast Carcinoma"],"enrollment":{"count":3177,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Health Education Program","otherNames":[],"type":"OTHER"},{"name":"Weight Loss Intervention","otherNames":[],"type":"OTHER"}],"last_update":"2026-09-02","lead_sponsor":"Alliance for Clinical Trials in Oncology","official_title":"Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women With Early Breast Cancer","overall_status":"ACTIVE_NOT_RECRUITING","phases":["PHASE3"],"primary_completion_date":{"date":"2030-05-30","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Invasive disease-free survival","timeFrame":"Up to 10 years"}],"references":[{"citation":"Liu Y, Xu S, Yang H, Wang Y. Multidimensional risk impact of obesity on breast cancer incidence, treatment, and prognosis. Int J Obes (Lond). 2026 Jun;50(6):1190-1198. doi: 10.1038/s41366-025-02008-9. Epub 2026 Jan 12.","pmid":"41526462","type":"DERIVED"},{"citation":"Ligibel JA, Ballman KV, McCall L, Goodwin PJ, Alfano CM, Bernstein V, Crane TE, Delahanty LM, Frank E, Hahn O, Hershman DL, Hopkins JO, Irwin M, Mayer EL, Minasian L, Nebeling L, Neuhouser ML, Paskett ED, Spears PA, Stearns V, Thomson CA, Weiss A, White J, Wadden TA, Winer EP, Hudis C, Partridge AH, Carey LA. Impact of a Weight Loss Intervention on 1-Year Weight Change in Women With Stage II/III Breast Cancer: Secondary Analysis of the Breast Cancer Weight Loss (BWEL) Trial. JAMA Oncol. 2025 Oct 1;11(10):1194-1203. doi: 10.1001/jamaoncol.2025.2738.","pmid":"40839373","type":"DERIVED"},{"citation":"Shaikh H, Bradhurst P, Ma LX, Tan SYC, Egger SJ, Vardy JL. Body weight management in overweight and obese breast cancer survivors. Cochrane Database Syst Rev. 2020 Dec 11;12(12):CD012110. doi: 10.1002/14651858.CD012110.pub2.","pmid":"33305350","type":"DERIVED"}],"start_date":{"date":"2016-09-16","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Breast Cancer WEight Loss Study (BWEL Study)","url":"https://clinicaltrials.gov/study/NCT02750826"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/bwel-nct02750826"}