# NP30179 (NCT03075696)

> A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

No report yet. It can be ordered.

## Registry

- Registry record: https://clinicaltrials.gov/study/NCT03075696
- Phase: PHASE1, PHASE2
- Status: ACTIVE_NOT_RECRUITING
- Sponsor: Hoffmann-La Roche
- Conditions: Non-Hodgkin's Lymphoma
- Interventions: Glofitamab; Obinutuzumab; Tocilizumab
- Enrollment: 940
- Primary outcome: Part I and II: Percentage of Participants With Dose Limiting Toxicities (DLTs)
- Primary outcome: Part I, II and III: Percentage of Participants With Adverse Events (AEs)
- Primary outcome: Part II: MTD or OBD of Glofitamab
- Primary outcome: Part II: Recommended Phase II Dose (RP2D) of Glofitamab
- Primary outcome: Part III: Complete Response (CR) Rate as Assessed by Independent Review Committee (IRC) According to Standard Non-hodgkin's Lymphoma (NHL) Response Criteria (Lugano Classification)
- Primary outcome: Part I, II and III: Area Under the Serum Concentration Versus Time Curve (AUC) of Glofitamab
- Primary outcome: Part I, II and III: Maximum Serum Concentration (Cmax) of Glofitamab
- Primary outcome: Part I, II and III: Minimum Serum Concentration (Cmin) of Glofitamab
- Primary outcome: Part I, II and III: Clearance (CL) of Glofitamab
- Primary outcome: Part I, II and III: Volume of Distribution at Steady-state (Vss) of Glofitamab
- Primary outcome: Part I, II and III: Half-life (t1/2) of Glofitamab

## Indexed commentary on NP30179 so far

Podcasts, YouTube videos and X posts we have indexed that name the trial. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.

- X threads: 9
- YouTube: 1
- Podcasts: 1

## Order

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## Free preview

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