{"commentary":{"count":12,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":6,"youtube":4,"podcast":2},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT03233711\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"NCT03233711","nct_id":"NCT03233711","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct03233711. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":750,"size":"focused","size_rule":"Focused: 1–12 commentary sources"},"registry":{"acronym":null,"arms":[{"description":"Patients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.","label":"Arm A (nivolumab)","type":"EXPERIMENTAL"},{"description":"Patients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.","label":"Arm B (clinical observation)","type":"OTHER"}],"collaborators":["Canadian Cancer Trials Group"],"completion_date":{"date":"2027-12-31","type":"ESTIMATED"},"conditions":["Anal Basaloid Carcinoma","Anal Canal Cloacogenic Carcinoma","Anal Margin Squamous Cell Carcinoma","Stage IIB Anal Cancer AJCC v8","Stage III Anal Cancer AJCC v8"],"enrollment":{"count":344,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Biopsy Procedure","type":"PROCEDURE"},{"name":"Biospecimen Collection","type":"PROCEDURE"},{"name":"Colonoscopy","type":"PROCEDURE"},{"name":"Computed Tomography","type":"PROCEDURE"},{"name":"Digital Rectal Examination","type":"PROCEDURE"},{"name":"High Resolution Anoscopy","type":"PROCEDURE"},{"name":"Magnetic Resonance Imaging","type":"PROCEDURE"},{"name":"Nivolumab","type":"BIOLOGICAL"},{"name":"Patient Observation","type":"OTHER"},{"name":"Proctoscopy","type":"PROCEDURE"},{"name":"Sigmoidoscopy","type":"PROCEDURE"},{"name":"X-Ray Imaging","type":"PROCEDURE"}],"last_update":"2026-10-01","lead_sponsor":"National Cancer Institute (NCI)","official_title":"A Randomized Phase III Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer","overall_status":"ACTIVE_NOT_RECRUITING","phases":["PHASE3"],"primary_completion_date":{"date":"2027-12-31","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Disease free survival","timeFrame":"Up to 5 years"}],"references":[],"start_date":{"date":"2018-07-05","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer","url":"https://clinicaltrials.gov/study/NCT03233711"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct03233711"}