{"preliminary_commentary":{"by_channel":{"x_thread":3,"youtube":1,"podcast":1,"x_video":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"small cell lung cancer with 1-10 brain metastases","name":"NCT03391362","nct_id":"NCT03391362","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct03391362. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"* Stereotactic radiation will begin within 14 days of the MRI used for radiation planning\n* Lesions \\<2 cm in maximum diameter will be treated with stereotactic radiosurgery, generally 20 Gy in 1 fraction\n* Lesions between 2.0 and 3.0 cm in maximum diameter will generally be treated to 18 Gy in 1 fraction\n* Lesions \\>3 cm will be generally be treated with stereotactic radiotherapy to 30 Gy in 5 fractions","label":"Stereotactic Radiation","type":"EXPERIMENTAL"}],"collaborators":["Dana-Farber Cancer Institute"],"completion_date":{"date":"2027-07-01","type":"ESTIMATED"},"conditions":["Brain Metastases","Small Cell Lung Cancer"],"enrollment":{"count":100,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"Stereotactic Radiation","otherNames":[],"type":"RADIATION"}],"last_update":"2026-09-29","lead_sponsor":"Brigham and Women's Hospital","official_title":"Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Single Arm, Phase II Trial","overall_status":"ACTIVE_NOT_RECRUITING","phases":["NA"],"primary_completion_date":{"date":"2024-04-10","type":"ACTUAL"},"primary_outcomes":[{"measure":"Neurologic Mortality","timeFrame":"12 months"}],"references":[{"citation":"Aizer AA, Tanguturi SK, Shi DD, Catalano PJ, Shin KY, Ricca I, Johnson M, Benham G, Kozono DE, Mak RH, Hertan L, Chipidza F, Krishnan M, Pashtan I, Peng L, Qian JM, Shiloh RY, Cagney DN, Sands J, Brown PD, Wen PY, Haas-Kogan DA, Rahman R. Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial. J Clin Oncol. 2025 Sep 20;43(27):2986-2997. doi: 10.1200/JCO-25-00056. Epub 2025 Jul 11.","pmid":"40644657","type":"RESULT"}],"start_date":{"date":"2018-02-23","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases","url":"https://clinicaltrials.gov/study/NCT03391362"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.1","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct03391362"}