{"preliminary_commentary":{"by_channel":{"x_thread":2,"youtube":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[["RMC-4630"]],"indication":"relapsed/refractory solid tumors","name":"NCT03634982","nct_id":"NCT03634982","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct03634982. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"RMC-4630 for oral administration","label":"RMC-4630","type":"EXPERIMENTAL"}],"collaborators":["Sanofi"],"completion_date":{"date":"2023-05-31","type":"ESTIMATED"},"conditions":["Solid Tumors"],"enrollment":{"count":133,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"RMC-4630","otherNames":[],"type":"DRUG"}],"last_update":"2022-09-01","lead_sponsor":"Revolution Medicines, Inc.","official_title":"A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants With Relapsed/Refractory Solid Tumors","overall_status":"UNKNOWN","phases":["PHASE1"],"primary_completion_date":{"date":"2023-03-31","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Number of participants with adverse events (AEs)","timeFrame":"up to 3 years"},{"measure":"Number of participants with dose limiting toxicities (DLTs)","timeFrame":"28 days"}],"references":[],"start_date":{"date":"2018-09-28","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors","url":"https://clinicaltrials.gov/study/NCT03634982"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct03634982"}