{"preliminary_commentary":{"by_channel":{"bluesky_thread":14,"x_thread":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT04897321\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"name":"NCT04897321","nct_id":"NCT04897321","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct04897321. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"During the treatment phase, the participant receives an infusion of the B7-H3-CAR T cells that were made in the Collection and Manufacturing Phase. Chemotherapy is given for several days prior to the cellular infusion. Patients are then monitored for possible side effects, as well as effects of the treatment on their cancer.","label":"Treatment Phase","type":"OTHER"}],"collaborators":[],"completion_date":{"date":"2028-03-01","type":"ESTIMATED"},"conditions":["Pediatric Solid Tumor","Osteosarcoma","Rhabdomyosarcoma","Neuroblastoma","Ewing Sarcoma","Wilms Tumor","Adrenocortical Cancer","Desmoplastic Small Round Cell Tumor","Germ Cell Cancer","Rhabdoid Tumor","Clear Cell Sarcoma","Hepatoblastoma","Melanoma","Carcinoma","Malignant Peripheral Nerve Sheath Tumors","Soft Tissue Sarcoma"],"enrollment":{"count":48,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Fludarabine","otherNames":["Fludara"],"type":"DRUG"},{"name":"Cyclophosphamide","otherNames":["Cytoxan"],"type":"DRUG"},{"name":"MESNA","otherNames":["Mesnex"],"type":"DRUG"},{"name":"B7-H3 CAR T cells","otherNames":["CAR T- cell infusion"],"type":"DRUG"}],"last_update":"2026-05-19","lead_sponsor":"St. Jude Children's Research Hospital","official_title":"B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)","overall_status":"RECRUITING","phases":["PHASE1"],"primary_completion_date":{"date":"2027-03-01","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Safety of B7-H3-CAR T cells","timeFrame":"6 weeks after B7-H3-CAR T cell infusion"}],"references":[],"start_date":{"date":"2022-07-06","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)","url":"https://clinicaltrials.gov/study/NCT04897321"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct04897321"}