{"preliminary_commentary":{"by_channel":{"x_thread":5},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[["carboplatin"]],"indication":"localized high-risk prostate cancer with germline BRCA1/2 mutations","name":"NCT05806515","nct_id":"NCT05806515","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=nct05806515. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Patients receive carboplatin IV on study. Patients then undergo surgery on study. Patients who experience PSA progression after surgery undergo CT or MRI of the abdomen and pelvis, CT of the chest or chest X-ray, or PSMA-PET throughout the trial. Patients also undergo collection of blood samples throughout the trial.","label":"Treatment (carboplatin)","type":"EXPERIMENTAL"}],"collaborators":["National Cancer Institute (NCI)"],"completion_date":{"date":"2031-06","type":"ESTIMATED"},"conditions":["Prostate Adenocarcinoma","Stage IIIB Prostate Cancer AJCC v8","Stage IIIC Prostate Cancer AJCC v8"],"enrollment":{"count":44,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Biospecimen Collection","otherNames":["Biological Sample Collection","Biospecimen Collected","Specimen Collection"],"type":"PROCEDURE"},{"name":"Carboplatin","otherNames":["Blastocarb","Carboplat","Carboplatin Hexal","Carboplatino","Carboplatinum","Carbosin","Carbosol","Carbotec","CBDCA","Displata","Ercar","JM-8","Nealorin","Novoplatinum","Paraplatin","Paraplatin AQ","Paraplatine","Platinwas","Ribocarbo"],"type":"DRUG"},{"name":"Chest Radiography","otherNames":["Chest X-ray"],"type":"PROCEDURE"},{"name":"Computed Tomography","otherNames":["CAT","CAT Scan","Computed Axial Tomography","Computerized Axial Tomography","Computerized Tomography","CT","CT Scan","tomography"],"type":"PROCEDURE"},{"name":"Magnetic Resonance Imaging","otherNames":["Magnetic Resonance","Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance","MR","MR Imaging","MRI","MRI Scan","NMR Imaging","NMRI","Nuclear Magnetic Resonance Imaging"],"type":"PROCEDURE"},{"name":"PSMA PET Scan","otherNames":["Prostate-specific Membrane Antigen PET","PSMA PET","PSMA-Positron emission tomography"],"type":"PROCEDURE"},{"name":"Surgical Procedure","otherNames":["Operation","Surgery","Surgery Type","Surgical","Surgical Intervention","Surgical Interventions","Surgical Procedures","Type of Surgery"],"type":"PROCEDURE"}],"last_update":"2026-01-29","lead_sponsor":"SWOG Cancer Research Network","official_title":"S2210 A Phase II Study of Neoadjuvant Carboplatin for Localized, High Risk Prostate Cancer With Germline BRCA1/2 Mutations","overall_status":"RECRUITING","phases":["PHASE2"],"primary_completion_date":{"date":"2027-07","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Pathologic complete response after neoadjuvant carboplatin","timeFrame":"Up to 5 years"}],"references":[],"start_date":{"date":"2024-03-01","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation","url":"https://clinicaltrials.gov/study/NCT05806515"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/nct05806515"}