{"preliminary_commentary":{"by_channel":{"x_thread":12,"podcast":2},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT04710628\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":{"generated_at":"2026-11-01T22:12:06.156Z","note":"Automated from all 14 indexed sources (Sep 2021 – Oct 2026). Each question is raised in at least two. Not an Erudio report: no source links. Not medical advice.","passages_read":14,"text":"- Whether PD-L1 predicts benefit from lenvatinib and pembrolizumab\n- Whether randomized evidence can clarify the regimen’s benefit relative to other options\n- How to manage treatment-related toxicity, including immune-related effects\n\nAlso discussed: lenvatinib dose intensity."},"drugs_tested":[["lenvatinib","pembrolizumab"]],"indication":"pretreated metastatic B3 thymoma and thymic carcinoma","name":"PECATI","nct_id":"NCT04710628","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=pecati-nct04710628. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"PECATI","arms":[{"description":"Pembrolizumab 200 mg will be administered to patients as 30-minute IV infusion every 3 weeks (a window of -5 minutes and +10 minutes is permitted).\n\nLenvatinib 20 mg (2 capsules of 10 mg) will be administered daily at the same time, with or without food. At the day 1 of each cycle, lenvatinib will be administered within 4 hours after finishing pembrolizumab (lenvatinib after pembrolizumab). Lenvatinib cannot be chewed","label":"PEMBROLIZUMAB + LENVATINIB","type":"EXPERIMENTAL"}],"collaborators":["Merck Sharp & Dohme LLC"],"completion_date":{"date":"2026-02-16","type":"ACTUAL"},"conditions":["Metastatic Thymic Carcinoma","Thymoma Type B3"],"enrollment":{"count":43,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Pembrolizumab","otherNames":["MK-3475, lambrolizumab"],"type":"DRUG"},{"name":"Lenvatinib 10 mg","otherNames":["E7080"],"type":"DRUG"}],"last_update":"2026-02-19","lead_sponsor":"MedSIR","official_title":"A Multicentric, Open-Label, Single Arm Phase II Study To Evaluate The Efficacy And Safety Of The Combination Of PEmbrolizumab And Lenvatinib In Pre-Treated Thymic Carcinoma PaTIents. PECATI.","overall_status":"COMPLETED","phases":["PHASE2"],"primary_completion_date":{"date":"2024-07-01","type":"ACTUAL"},"primary_outcomes":[{"measure":"Progression-free survival (PFS)","timeFrame":"5 months"}],"references":[{"citation":"Remon J, Bironzo P, Girard N, Bigay-Game L, Juan-Vidal O, de Castro J, Reguart N, Greillier L, Cousin S, Dansin E, Majem M, Bernabe R, Mosquera Martinez J, Diaz M, Meya A, Alcala-Lopez D, Garcia-Sanz A, Righi L, Novello S, Besse B. Lenvatinib plus pembrolizumab in pretreated metastatic B3 thymoma and thymic carcinoma (PECATI): a single-arm, phase 2 trial. Lancet Oncol. 2025 Sep;26(9):1215-1226. doi: 10.1016/S1470-2045(25)00300-6.","pmid":"40907517","type":"DERIVED"}],"start_date":{"date":"2021-09-21","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents","url":"https://clinicaltrials.gov/study/NCT04710628"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.1","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/pecati-nct04710628"}