{"preliminary_commentary":{"by_channel":{"x_thread":5,"podcast":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"prostate cancer with biochemical failure after radical prostatectomy","name":"PERYTON","nct_id":"NCT04642027","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=peryton-nct04642027. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"PERYTON","arms":[{"description":"Conventional sEBRT","label":"Conventional","type":"ACTIVE_COMPARATOR"},{"description":"Hypofractionated sEBRT","label":"Hypofractionation","type":"EXPERIMENTAL"}],"collaborators":["Dutch Cancer Society"],"completion_date":{"date":"2030-09-01","type":"ESTIMATED"},"conditions":["Prostate Cancer","Cancer Recurrence"],"enrollment":{"count":538,"type":"ESTIMATED"},"has_results":false,"interventions":[{"name":"Conventional sEBRT","otherNames":["Conventional salvage external beam radiation therapy"],"type":"RADIATION"},{"name":"Hypofractionated sEBRT","otherNames":["Hypofractionated salvage external beam radiation therapy"],"type":"RADIATION"}],"last_update":"2024-02-28","lead_sponsor":"University Medical Center Groningen","official_title":"PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy of Biochemical Failure After Radical Prostatectomy for Prostate Cancer","overall_status":"RECRUITING","phases":["PHASE3"],"primary_completion_date":{"date":"2029-09-01","type":"ESTIMATED"},"primary_outcomes":[{"measure":"5-year progression-free survival","timeFrame":"5 years"}],"references":[{"citation":"Staal FHE, Janssen J, Oprea-Lager DE, Engelen AM, van Limbergen EJ, Smeenk RJ, de Jong MAA, Budiharto TCG, Jacobs I, Haverkort DMAD, Brouwer CL, Ng Wei Siang K, Langendijk JA, Verzijlbergen JF, de Jong IJ, Noordzij W, Aluwini S. Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography-Based Clinical Target Volume Delineation Guideline for Postprostatectomy Salvage Radiation Therapy: The PERYTON Guideline. Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):688-696. doi: 10.1016/j.ijrobp.2023.09.016. Epub 2023 Sep 18.","pmid":"37729971","type":"DERIVED"},{"citation":"Staal FHE, Janssen J, Brouwer CL, Langendijk JA, Ng Wei Siang K, Schuit E, de Jong IJ, Verzijlbergen JF, Smeenk RJ, Aluwini S. Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol. BMC Cancer. 2022 Apr 15;22(1):416. doi: 10.1186/s12885-022-09493-5.","pmid":"35428210","type":"DERIVED"}],"start_date":{"date":"2020-09-01","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy","url":"https://clinicaltrials.gov/study/NCT04642027"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/peryton-nct04642027"}