{"preliminary_commentary":{"by_channel":{"x_thread":23,"podcast":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT00769405\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":null,"drugs_tested":[["oxaliplatin"]],"indication":"colorectal peritoneal metastases","name":"PRODIGE 7","nct_id":"NCT00769405","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=prodige-7-nct00769405. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 301+ verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Patients undergo surgery and receive standard systemic chemotherapy comprising leucovorin calcium IV followed by fluorouracil IV over 30 minutes. Systemic chemotherapy will continue for at least 6 months (before and after surgery). Patients also undergo CHIP comprising oxaliplatin intraperitoneally during surgery and hyperthermia for 30 minutes.","label":"Arm I","type":"EXPERIMENTAL"},{"description":"Patients undergo surgery and receive standard systemic chemotherapy comprising leucovorin calcium IV followed by fluorouracil IV over 30 minutes. Systemic chemotherapy will continue for at least 6 months (before and after surgery).","label":"Arm II","type":"EXPERIMENTAL"}],"collaborators":[],"completion_date":null,"conditions":["Colorectal Cancer","Primary Peritoneal Cavity Cancer"],"enrollment":{"count":264,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"fluorouracil","otherNames":[],"type":"DRUG"},{"name":"leucovorin calcium","otherNames":[],"type":"DRUG"},{"name":"oxaliplatin","otherNames":[],"type":"DRUG"},{"name":"hyperthermia treatment","otherNames":[],"type":"PROCEDURE"}],"last_update":"2016-08-30","lead_sponsor":"UNICANCER","official_title":"Phase III Study Evaluating the Use of Systemic Chemotherapy and Chemohyperthemia Intraperitoneal Preoperatively (CHIP) and After Maximum Resection of Peritoneal Carcinomatosis Originating With Colorectal Cancer","overall_status":"COMPLETED","phases":["PHASE3"],"primary_completion_date":{"date":"2015-12","type":"ACTUAL"},"primary_outcomes":[{"measure":"Overall survival","timeFrame":"until 3 years"}],"references":[{"citation":"Quenet F, Elias D, Roca L, Goere D, Ghouti L, Pocard M, Facy O, Arvieux C, Lorimier G, Pezet D, Marchal F, Loi V, Meeus P, Juzyna B, de Forges H, Paineau J, Glehen O; UNICANCER-GI Group and BIG Renape Group. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021 Feb;22(2):256-266. doi: 10.1016/S1470-2045(20)30599-4. Epub 2021 Jan 18.","pmid":"33476595","type":"DERIVED"}],"start_date":{"date":"2008-02"},"study_type":"INTERVENTIONAL","title":"Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer","url":"https://clinicaltrials.gov/study/NCT00769405"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.1","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/prodige-7-nct00769405"}