{"preliminary_commentary":{"by_channel":{"x_thread":41,"podcast":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT00687986\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":null,"drugs_tested":[],"indication":"stage IA NSCLC","name":"ROSEL","nct_id":"NCT00687986","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=rosel-nct00687986. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":1950,"size":"deep","size_rule":"Deep: 301+ verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"ROSEL","arms":[{"description":"primary surgical resection","label":"primary surgery","type":"ACTIVE_COMPARATOR"},{"description":"primary stereotactic radiotherapy","label":"stereotactic radiotherapy","type":"EXPERIMENTAL"}],"collaborators":["ZonMw: The Netherlands Organisation for Health Research and Development"],"completion_date":{"date":"2010-02","type":"ACTUAL"},"conditions":["Lung Cancer"],"enrollment":{"count":22,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"stereotactic radiotherapy","otherNames":["radiotherapy"],"type":"RADIATION"},{"name":"primary surgery","otherNames":["operation"],"type":"PROCEDURE"}],"last_update":"2022-03-17","lead_sponsor":"Amsterdam UMC, location VUmc","official_title":"A Randomized Clinical Trial of Surgery Versus Radiosurgery (Stereotactic Radiotherapy) in Patients With Stage IA NSCLC Who Are Fit to Undergo Primary Resection","overall_status":"TERMINATED","phases":["PHASE3"],"primary_completion_date":{"date":"2010-02","type":"ACTUAL"},"primary_outcomes":[{"measure":"local and regional control","timeFrame":"5 years"}],"references":[{"citation":"Haasbeek CJ, Senan S, Smit EF, Paul MA, Slotman BJ, Lagerwaard FJ. Critical review of nonsurgical treatment options for stage I non-small cell lung cancer. Oncologist. 2008 Mar;13(3):309-19. doi: 10.1634/theoncologist.2007-0195.","pmid":"18378542","type":"BACKGROUND"},{"citation":"Hurkmans CW, Cuijpers JP, Lagerwaard FJ, Widder J, van der Heide UA, Schuring D, Senan S. Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study. Radiat Oncol. 2009 Jan 12;4:1. doi: 10.1186/1748-717X-4-1.","pmid":"19138400","type":"BACKGROUND"},{"citation":"Chang JY, Senan S, Paul MA, Mehran RJ, Louie AV, Balter P, Groen HJ, McRae SE, Widder J, Feng L, van den Borne BE, Munsell MF, Hurkmans C, Berry DA, van Werkhoven E, Kresl JJ, Dingemans AM, Dawood O, Haasbeek CJ, Carpenter LS, De Jaeger K, Komaki R, Slotman BJ, Smit EF, Roth JA. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015 Jun;16(6):630-7. doi: 10.1016/S1470-2045(15)70168-3. Epub 2015 May 13.","pmid":"25981812","type":"BACKGROUND"},{"citation":"Louie AV, van Werkhoven E, Chen H, Smit EF, Paul MA, Widder J, Groen HJ, van den Borne BE, De Jaeger K, Slotman BJ, Senan S. Patient reported outcomes following stereotactic ablative radiotherapy or surgery for stage IA non-small-cell lung cancer: Results from the ROSEL multicenter randomized trial. Radiother Oncol. 2015 Oct;117(1):44-8. doi: 10.1016/j.radonc.2015.08.011.","pmid":"26492839","type":"BACKGROUND"},{"citation":"Park S, Kim HJ, Park IK, Kim YT, Kang CH. Stereotactic ablative radiotherapy versus surgery in older patients with stage I lung cancer. Eur J Cardiothorac Surg. 2021 Jul 14;60(1):74-80. doi: 10.1093/ejcts/ezab045.","pmid":"33668061","type":"DERIVED"}],"start_date":{"date":"2008-10"},"study_type":"INTERVENTIONAL","title":"Trial of Either Surgery or Stereotactic Radiotherapy for Early Stage (IA) Lung Cancer","url":"https://clinicaltrials.gov/study/NCT00687986"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/rosel-nct00687986"}