{"preliminary_commentary":{"by_channel":{"x_thread":4,"youtube":1},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"brain metastases","name":"RTOG 0933","nct_id":"NCT01227954","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=rtog-0933-nct01227954. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":null,"arms":[{"description":"Whole brain radiotherapy (WBRT) with hippocampal avoidance using intensity-modulated radiation therapy (IMRT)","label":"WBRT with Hippocampal Avoidance","type":"OTHER"}],"collaborators":["National Cancer Institute (NCI)","NRG Oncology"],"completion_date":{"date":"2016-12","type":"ACTUAL"},"conditions":["Cognitive/Functional Effects","Metastatic Cancer","Unspecified Adult Solid Tumor, Protocol Specific"],"enrollment":{"count":113,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"intensity-modulated radiation therapy","otherNames":["IMRT"],"type":"RADIATION"}],"last_update":"2017-09-27","lead_sponsor":"Radiation Therapy Oncology Group","official_title":"A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases","overall_status":"COMPLETED","phases":["PHASE2"],"primary_completion_date":{"date":"2013-05","type":"ACTUAL"},"primary_outcomes":[{"measure":"Percent Change in Delayed Recall at 4 Months as Measured by the Hopkins Verbal Learning Test-Revised (HVLT-R)","timeFrame":"Baseline and 4 months from start of treatment"}],"references":[{"citation":"Gondi V, Pugh SL, Tome WA, Caine C, Corn B, Kanner A, Rowley H, Kundapur V, DeNittis A, Greenspoon JN, Konski AA, Bauman GS, Shah S, Shi W, Wendland M, Kachnic L, Mehta MP. Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases (RTOG 0933): a phase II multi-institutional trial. J Clin Oncol. 2014 Dec 1;32(34):3810-6. doi: 10.1200/JCO.2014.57.2909. Epub 2014 Oct 27.","pmid":"25349290","type":"RESULT"}],"start_date":{"date":"2011-03"},"study_type":"INTERVENTIONAL","title":"Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases","url":"https://clinicaltrials.gov/study/NCT01227954"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/rtog-0933-nct01227954"}