{"commentary":{"count":111,"free_build_floor":8,"listing_floor":3,"by_channel":{"x_thread":76,"podcast":18,"youtube":17},"note":"Indexed podcasts, YouTube videos and X posts that name this trial. A report screens them, searches for more and cites what clinicians said when it is built."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT01446744\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's public preview; the full report is still bought."},"name":"SABR-COMET","nct_id":"NCT01446744","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=sabr-comet-nct01446744. The price is fixed at order. We build the report after the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1950,"size":"deep","size_rule":"Deep: 41+ commentary sources"},"registry":{"acronym":"SABR-COMET","arms":[{"description":"Standard of care, palliative radiotherapy, and chemotherapy at the discretion of the treating medical oncologist","label":"Standard arm","type":"ACTIVE_COMPARATOR"},{"description":"Stereotactic ablative radiotherapy, and chemotherapy at the discretion of the treating medical oncologist","label":"Stereotactic arm","type":"EXPERIMENTAL"}],"collaborators":["London Regional Cancer Program, Canada","VU University of Amsterdam"],"completion_date":{"date":"2026-06","type":"ESTIMATED"},"conditions":["Metastatic Tumors"],"enrollment":{"count":99,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"Stereotactic ablative radiotherapy","type":"RADIATION"},{"name":"palliative radiotherapy","type":"RADIATION"}],"last_update":"2023-10-05","lead_sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","official_title":"Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic Tumors (SABR-COMET): A Randomized Phase II Trial","overall_status":"UNKNOWN","phases":["PHASE2"],"primary_completion_date":{"date":"2026-06","type":"ESTIMATED"},"primary_outcomes":[{"measure":"Overall Survival","timeFrame":"At approximately end of year 4 (study completion)"}],"references":[{"citation":"Palma DA, Olson R, Harrow S, Gaede S, Louie AV, Haasbeek C, Mulroy L, Lock M, Rodrigues GB, Yaremko BP, Schellenberg D, Ahmad B, Senthi S, Swaminath A, Kopek N, Liu M, Moore K, Currie S, Schlijper R, Bauman GS, Laba J, Qu XM, Warner A, Senan S. Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized Trial. J Clin Oncol. 2020 Sep 1;38(25):2830-2838. doi: 10.1200/JCO.20.00818. Epub 2020 Jun 2.","pmid":"32484754","type":"DERIVED"},{"citation":"Palma DA, Olson R, Harrow S, Gaede S, Louie AV, Haasbeek C, Mulroy L, Lock M, Rodrigues GB, Yaremko BP, Schellenberg D, Ahmad B, Griffioen G, Senthi S, Swaminath A, Kopek N, Liu M, Moore K, Currie S, Bauman GS, Warner A, Senan S. Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial. Lancet. 2019 May 18;393(10185):2051-2058. doi: 10.1016/S0140-6736(18)32487-5. Epub 2019 Apr 11.","pmid":"30982687","type":"DERIVED"},{"citation":"Palma DA, Haasbeek CJ, Rodrigues GB, Dahele M, Lock M, Yaremko B, Olson R, Liu M, Panarotto J, Griffioen GH, Gaede S, Slotman B, Senan S. Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): study protocol for a randomized phase II trial. BMC Cancer. 2012 Jul 23;12:305. doi: 10.1186/1471-2407-12-305.","pmid":"22823994","type":"DERIVED"}],"start_date":{"date":"2011-11"},"study_type":"INTERVENTIONAL","title":"Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic Tumors (SABR-COMET)","url":"https://clinicaltrials.gov/study/NCT01446744"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"2.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/sabr-comet-nct01446744"}