{"preliminary_commentary":{"by_channel":{"x_thread":3},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":false},"commentary_summary":null,"drugs_tested":[],"indication":"low-risk early-stage cervical cancer","name":"SHAPE","nct_id":"NCT01658930","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=shape-nct01658930. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"SHAPE","arms":[{"description":null,"label":"Radical Hysterectomy","type":"ACTIVE_COMPARATOR"},{"description":null,"label":"Simple Hysterectomy","type":"EXPERIMENTAL"}],"collaborators":["Gynecologic Cancer Intergroup (GCIG)","Canadian Institutes of Health Research (CIHR)","Korean Gynecologic Oncology Group","Dutch Gynaecological Oncology Group","Cancer Trials Ireland","Arbeitsgemeinschaft Gynaekologische Onkologie Austria","Belgian Gynaecological Oncology Group","ARCAGY/ GINECO GROUP","Institute of Cancer Research, United Kingdom","Shanghai Cancer Centre","P. Herzen Moscow Oncology Research Institute","Arbeitsgemeinschaft Gynaekologische Onkologie Studiengruppe Ovarialkarzinom Germany","Institut Universitaire du Cancer de Toulouse"],"completion_date":{"date":"2024-11-04","type":"ACTUAL"},"conditions":["Cervical Cancer"],"enrollment":{"count":700,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"Radical Hysterectomy + pelvic lymph node dissection","otherNames":[],"type":"PROCEDURE"},{"name":"Simple hysterectomy + pelvic lymph node dissection","otherNames":[],"type":"PROCEDURE"}],"last_update":"2024-12-17","lead_sponsor":"Canadian Cancer Trials Group","official_title":"A Randomized Phase III Trial Comparing Radical Hysterectomy and Pelvic Node Dissection vs Simple Hysterectomy and Pelvic Node Dissection in Patients With Low-Risk Early Stage Cervical Cancer (SHAPE)","overall_status":"COMPLETED","phases":["NA"],"primary_completion_date":{"date":"2023-03-11","type":"ACTUAL"},"primary_outcomes":[{"measure":"Pelvic Recurrence Rate at 3 Years","timeFrame":"3 years"}],"references":[{"citation":"Plante M, Kwon JS, Ferguson S, Samouelian V, Ferron G, Maulard A, de Kroon C, Van Driel W, Tidy J, Williamson K, Mahner S, Kommoss S, Goffin F, Tamussino K, Eyjolfsdottir B, Kim JW, Gleeson N, Brotto L, Tu D, Shepherd LE; CX.5 SHAPE investigators; CX.5 SHAPE Investigators. Simple versus Radical Hysterectomy in Women with Low-Risk Cervical Cancer. N Engl J Med. 2024 Feb 29;390(9):819-829. doi: 10.1056/NEJMoa2308900.","pmid":"38416430","type":"RESULT"},{"citation":"Kwon JS, McTaggart-Cowan H, Ferguson SE, Samouelian V, Lambaudie E, Guyon F, Tidy J, Williamson K, Gleeson N, de Kroon C, van Driel W, Mahner S, Hanker L, Goffin F, Berger R, Eyjolfsdottir B, Kim JW, Brotto LA, Pataky R, Yeung SST, Chan KKW, Cheung MC, Ubi J, Tu D, Shepherd LE, Plante M. Cost-effectiveness analysis of simple hysterectomy compared to radical hysterectomy for early cervical cancer: analysis from the GCIG/CCTG CX.5/SHAPE trial. J Gynecol Oncol. 2024 Nov;35(6):e117. doi: 10.3802/jgo.2024.35.e117. Epub 2024 Oct 18.","pmid":"39453395","type":"DERIVED"},{"citation":"Ferguson SE, Brotto LA, Kwon J, Samouelian V, Ferron G, Maulard A, Kroon C, Driel WV, Tidy J, Williamson K, Mahner S, Kommoss S, Goffin F, Tamussino K, Eyjolfsdottir B, Kim JW, Gleeson N, Tu D, Shepherd L, Plante M. Sexual Health and Quality of Life in Patients With Low-Risk Early-Stage Cervical Cancer: Results From GCIG/CCTG CX.5/SHAPE Trial Comparing Simple Versus Radical Hysterectomy. J Clin Oncol. 2025 Jan 10;43(2):167-179. doi: 10.1200/JCO.24.00440. Epub 2024 Oct 1.","pmid":"39353164","type":"DERIVED"},{"citation":"Boisen M, Guido R. Emerging Treatment Options for Cervical Dysplasia and Early Cervical Cancer. Clin Obstet Gynecol. 2023 Sep 1;66(3):500-515. doi: 10.1097/GRF.0000000000000790. Epub 2023 Jul 25.","pmid":"37650664","type":"DERIVED"}],"start_date":{"date":"2012-12-10","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Radical Versus Simple Hysterectomy and Pelvic Node Dissection With Low-risk Early Stage Cervical Cancer","url":"https://clinicaltrials.gov/study/NCT01658930"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/shape-nct01658930"}