{"preliminary_commentary":{"by_channel":{"x_thread":9},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. This is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT04939246\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"commentary_summary":null,"drugs_tested":[],"indication":"inoperable primary or metastatic carcinoma","name":"SMART ONE","nct_id":"NCT04939246","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=smart-one-nct04939246. The price is an estimate of verified statements from the commentary indexed so far. Final coverage is set when the report is built. You never pay more than quoted: if the report is delivered at a smaller size, you pay that size's price, and anything paid above it is refunded. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_rule":"Never more than quoted: the buyer pays the smaller of price_usd and the price the delivered edition is sold at.","price_usd":750,"size":"focused","size_rule":"Focused: 1–150 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"SMART ONE","arms":[{"description":"Patients will receive SABR in a single-fraction regiment treatment with one single dose of radiation therapy per lesion. Patients may be treated for up to a total of ten lesions. Each lesion will be treated in one fraction.","label":"Single-fraction SABR","type":"OTHER"}],"collaborators":["Viewray Inc."],"completion_date":{"date":"2024-07-17","type":"ACTUAL"},"conditions":["Metastatic Carcinoma"],"enrollment":{"count":30,"type":"ACTUAL"},"has_results":true,"interventions":[{"name":"Stereotactic ablative body radiation therapy","otherNames":[],"type":"RADIATION"}],"last_update":"2025-07-17","lead_sponsor":"Baptist Health South Florida","official_title":"A Feasibility Study of Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) in One Fraction for Inoperable Primary or Metastatic Carcinoma (SMART ONE)","overall_status":"COMPLETED","phases":["NA"],"primary_completion_date":{"date":"2024-07-17","type":"ACTUAL"},"primary_outcomes":[{"measure":"Number of Participants With SABR Successfully Delivered in One Fraction","timeFrame":"through study completion, an average of 1 year"},{"measure":"Number of Patients Demonstrating Tolerability","timeFrame":"through study completion, an average of 1 year"}],"references":[{"citation":"Chuong MD, Mittauer KE, Bassetti MF, Rojas C, Glide-Hurst C, Kalman NS, Tom MC, Rubens M, Crosby J, Burr A, Tolakanahalli R, Gutierrez AN, Bassiri N, Mehta MP, Kotecha R. Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy in One Fraction (SMART ONE): A Multicenter, Single-Arm, Phase 2 Trial. Int J Radiat Oncol Biol Phys. 2025 Jul 15;122(4):957-967. doi: 10.1016/j.ijrobp.2025.03.030. Epub 2025 Mar 28.","pmid":"40158734","type":"RESULT"}],"start_date":{"date":"2021-06-18","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) in One Fraction","url":"https://clinicaltrials.gov/study/NCT04939246"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.2","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/smart-one-nct04939246"}