{"preliminary_commentary":{"by_channel":{"x_thread":10,"podcast":4,"youtube":3},"note":"Preliminary. Indexed podcasts, YouTube videos and X posts that name this trial so far. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build."},"free_build":{"available":true,"how":"POST https://www.erudio.com/api/trial-requests with {\"nct_id\": \"NCT01099423\", \"email\": \"<work email>\"}. The person who owns that inbox must confirm by the emailed link; agents cannot confirm. The result is the report's free public preview; the full report is still bought."},"name":"SURTIME","nct_id":"NCT01099423","offer":{"currency":"USD","how":"Order at https://www.erudio.com/contact?report=surtime-nct01099423. The price is an estimate of verified statements from the commentary indexed so far, fixed at order. Final coverage is set when the report is built. We build the report within 24 hours of confirming the order and deliver it when it passes our checks; if it cannot be built to our standard, nothing is charged.","price_usd":1250,"size":"standard","size_rule":"Standard: 151–300 verified statements, estimated at 14 per indexed commentary source"},"registry":{"acronym":"SURTIME","arms":[{"description":"Surgery followed by Sunitinib","label":"Immediate nephrectomy","type":"ACTIVE_COMPARATOR"},{"description":"Sunitinib (3 cycles) followed by surgery followed by Sunitinib","label":"Deferred nephrectomy","type":"EXPERIMENTAL"}],"collaborators":["Wales Cancer Trials Unit","Canadian Urologic Oncology Group","Institute of Cancer Research, United Kingdom"],"completion_date":{"date":"2017-05","type":"ESTIMATED"},"conditions":["Kidney Cancer"],"enrollment":{"count":99,"type":"ACTUAL"},"has_results":false,"interventions":[{"name":"timing of surgery","otherNames":[],"type":"PROCEDURE"},{"name":"gene expression analysis","otherNames":[],"type":"GENETIC"},{"name":"biologic sample preservation procedure","otherNames":[],"type":"OTHER"},{"name":"laboratory biomarker analysis","otherNames":[],"type":"OTHER"},{"name":"therapeutic conventional surgery","otherNames":[],"type":"PROCEDURE"}],"last_update":"2017-02-08","lead_sponsor":"European Organisation for Research and Treatment of Cancer - EORTC","official_title":"Randomized Phase III Trial Comparing Immediate Versus Deferred Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma","overall_status":"UNKNOWN","phases":["PHASE3"],"primary_completion_date":{"date":"2016-04","type":"ACTUAL"},"primary_outcomes":[{"measure":"Overall progression-free survival","timeFrame":null}],"references":[{"citation":"Bex A, Mulders P, Jewett M, Wagstaff J, van Thienen JV, Blank CU, van Velthoven R, Del Pilar Laguna M, Wood L, van Melick HHE, Aarts MJ, Lattouf JB, Powles T, de Jong Md PhD IJ, Rottey S, Tombal B, Marreaud S, Collette S, Collette L, Haanen J. Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial. JAMA Oncol. 2019 Feb 1;5(2):164-170. doi: 10.1001/jamaoncol.2018.5543.","pmid":"30543350","type":"DERIVED"},{"citation":"Leon L, Garcia-Figueiras R, Suarez C, Arjonilla A, Puente J, Vargas B, Mendez Vidal MJ, Sebastia C. Recommendations for the clinical and radiological evaluation of response to treatment in metastatic renal cell cancer. Target Oncol. 2014 Mar;9(1):9-24. doi: 10.1007/s11523-013-0304-7. Epub 2013 Dec 12.","pmid":"24338498","type":"DERIVED"},{"citation":"Winquist E, Rodrigues G. Open clinical uro-oncology trials in Canada. Can J Urol. 2012 Dec;19(6):6587-91. No abstract available.","pmid":"23228299","type":"DERIVED"}],"start_date":{"date":"2010-04","type":"ACTUAL"},"study_type":"INTERVENTIONAL","title":"Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Cancer","url":"https://clinicaltrials.gov/study/NCT01099423"},"report":null,"schema_id":"erudio.trial_listing","schema_version":"3.0","state":"listed","state_text":"No report yet. It can be ordered.","url":"https://www.erudio.com/trials/surtime-nct01099423"}