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Clinical trial · no report yet · Phase 3

DAWN-303

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube1
Podcasts1
X threads1

The trial

ClinicalTrials.gov
Official title
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Phase
Phase 3
Status
Recruiting
Conditions
Solid Tumors
Interventions
INCB161734; Placebo; Investigator's choice of chemotherapy
Arms
  • INCB161734 plus chemotherapy · Experimental
  • Placebo plus chemotherapy · Experimental
Enrollment
588 (estimated)
Primary outcomes
  • Overall Survival (OS)
  • Progression-free survival (PFS) by BICR
  • Objective Response by BICR
Sponsor
Incyte Corporation with Qiagen Manchester Ltd
Start
Apr 9, 2026
Primary completion
Sep 15, 2028 (estimated)
Results posted
No
Registry record
NCT07522073 · updated Oct 8, 2026