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Clinical trial · no report yet · Phase 2

IFM 2022-01

Minimal Residual Disease-based Strategy With T-Cell Redirector After Treatment With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (D-VRd) in Newly Diagnosed Multiple Myeloma

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads4
YouTube1

The trial

ClinicalTrials.gov
Official title
Minimal Residual Disease-based Strategy With T-Cell Redirector After Treatment With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (D-VRd) in Newly Diagnosed Multiple Myeloma: A Phase 2 (IFM 2022-01)
Phase
Phase 2
Status
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
Teclistamab; Talquetamab; Lenalidomide; Bortezomib; Daratumumab; Dexamethasone
Arms
  • Teclistamab and Lenalidomide · Experimental
  • Talquetamab andTeclistamab · Experimental
Enrollment
103 (estimated)
Primary outcomes
  • Rate of sustained MRD negativity (NGS, 10^-5)
  • Rate of conversion from positive MRD to negative MRD (NGS, 10^-5)
Sponsor
Nantes University Hospital with Janssen Pharmaceutica
Start
Jun 26, 2024
Primary completion
Apr 26, 2028 (estimated)
Results posted
No
Registry record
NCT06353022 · updated Mar 17, 2026