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Clinical trial · no report yet · Phase 1

JYP0322

Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of JYP0322 in Patients With Solid Tumors
Phase
Phase 1
Status
Recruiting
Conditions
Protein Kinase Inhibitors; Other Protocol Specified Criteria; Lung Neoplasms; Brain Neoplasms
Interventions
JYP0322 50 mg qd; JYP0322 100 mg qd; JYP0322 200 mg qd; JYP0322 100 mg bid; JYP0322 150 mg bid; JYP0322 200 mg bid; JYP0322 150mg tid
Arms
  • 50 mg qd · Experimental
  • 100 mg qd · Experimental
  • 200 mg qd · Experimental
  • 100 mg bid · Experimental
  • 150 mg bid · Experimental
  • 200 mg bid · Experimental
  • 150 mg tid · Experimental
Enrollment
101 (estimated)
Primary outcomes
  • The frequency and severity of adverse events of JYP0322
Sponsor
Guangzhou JOYO Pharma Co., Ltd
Start
May 4, 2022
Primary completion
Jun 30, 2026 (estimated)
Results posted
No
Registry record
NCT06128148 · updated Jul 14, 2025