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Clinical trial · no report yet · Phase 3

Krascendo 1

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

  • NCT06497556 ↗
  • Active not recruiting
  • Hoffmann-La Roche
  • 18 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads18

The trial

ClinicalTrials.gov
Official title
A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Patients With Previously Treated KRAS G12C-Positive Advanced or Metastatic Non-Small Cell Lung Cancer
Phase
Phase 3
Status
Active not recruiting
Conditions
Non-Small Cell Lung Cancer; KRAS G12C Lung Cancer
Interventions
Divarasib; Sotorasib; Adagrasib
Arms
  • Divarasib · Experimental
  • KRAS G12C inhibitor · Active comparator
Enrollment
338
Primary outcomes
  • Progression-Free Survival (PFS)
Sponsor
Hoffmann-La Roche with Chugai Pharmaceutical
Start
Sep 23, 2024
Primary completion
May 19, 2026
Results posted
No
Registry record
NCT06497556 · updated Sep 16, 2026