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Clinical trial · no report yet · Phase 3

MagnetisMM-6

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube10
X threads8
Podcasts4

The trial

ClinicalTrials.gov
Official title
AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE VERSUS DARATUMUMAB + BORTEZOMIB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
Phase
Phase 3
Status
Recruiting
Conditions
Multiple Myeloma
Interventions
Elranatamab; Daratumumab; Lenalidomide; Dexamethasone; Bortezomib
Arms
  • Part 1, Dose Level 1: Elranatamab + Daratumumab + Lenalidomide · Experimental
  • Part 1, Multiple Dose Levels, Elranatamab + Daratumumab + Lenalidomide · Experimental
  • Part 2 Randomized Arm A: Elranatamab + Daratumumab + Lenalidomide · Experimental
  • Part 2 Randomized Arm B: Daratumumab + Bortezomib + Lenalidomide + Dexamethasone · Active comparator
  • Part 1: Elranatamab + Lenalidomide · Experimental
Enrollment
1,060 (estimated)
Primary outcomes
  • Part 1 Dose Limiting Toxicity
  • Part 2: Progression free survival per IMWG
  • Part 2: Minimal Residual Disease negative CR rate
Sponsor
Pfizer
Start
Nov 10, 2022
Primary completion
Oct 18, 2030 (estimated)
Results posted
No
Registry record
NCT05623020 · updated Sep 25, 2026