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Clinical trial · no report yet · Phase 2

NCT01824875

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

  • NCT01824875 ↗
  • Completed
  • ECOG-ACRIN Cancer Research Group
  • 11 commentary sources found
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube4
X threads4
Podcasts3

The trial

ClinicalTrials.gov
Official title
A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors
Phase
Phase 2
Status
Completed
Conditions
Gastrinoma; Glucagonoma; Insulinoma; Islet Cell Carcinoma; Pancreatic Polypeptide Tumor; Recurrent Islet Cell Carcinoma; Somatostatinoma
Interventions
temozolomide; capecitabine
Arms
  • Arm A (temozolomide) · Experimental
  • Arm B (temozolomide and capecitabine) · Experimental
Enrollment
144
Primary outcomes
  • Progression-free Survival
Sponsor
ECOG-ACRIN Cancer Research Group with National Cancer Institute (NCI)
Start
Aug 8, 2013
Primary completion
May 26, 2021
Results posted
Yes
Registry record
NCT01824875 · updated Sep 29, 2026

Publications

linked from the registry
  • Kunz PL, Graham NT, Catalano PJ, Nimeiri HS, Fisher GA, Longacre TA, Suarez CJ, Martin BA, Yao JC, Kulke MH, Hendifar AE, Shanks JC, Shah MH, Zalupski MM, Schmulbach EL, Reidy-Lagunes DL, Strosberg JR, O'Dwyer PJ, Benson AB 3rd. Randomized Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors (ECOG-ACRIN E2211). J Clin Oncol. 2023 Mar 1;41(7):1359-1369. doi: 10.1200/JCO.22.01013. Epub 2022 Oct 19. PubMed 36260828