Clinical trial · no report yet · Phase 2
NCT03137771
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
- NCT03137771 ↗
- Active not recruiting
- NRG Oncology
- 113 commentary sources found
- Deep
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.
| Channel | Found | |
|---|---|---|
| X threads | 81 | |
| YouTube | 22 | |
| Podcasts | 10 |
The trial
ClinicalTrials.gov- Official title
- Maintenance Systemic Therapy Versus Local Consolidative Therapy (LCT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial
- Phase
- Phase 2
- Status
- Active not recruiting
- Conditions
- Recurrent Non-Small Cell Lung Carcinoma; Stage IV Non-Small Cell Lung Cancer
- Interventions
- 3-Dimensional Conformal Radiation Therapy (3D-CRT); Docetaxel; Gemcitabine; Intensity-Modulated Radiation Therapy (IMRT); Pemetrexed Disodium; Stereotactic Body Radiation Therapy (SBRT); Erlotinib Hydrochloride; Pembrolizumab
- Arms
- Arm 1 (systemic maintenance chemotherapy) · Active comparator
- Arm 2 (LCT + systemic maintenance chemotherapy) · Experimental
- Enrollment
- 218
- Primary outcomes
- [Phase II] Progression-free Survival
- [Phase III] Overall Survival
- Sponsor
- NRG Oncology with National Cancer Institute (NCI)
- Start
- Apr 7, 2017
- Primary completion
- Dec 20, 2023
- Results posted
- Yes
- Registry record
- NCT03137771 · updated Jun 8, 2026
Publications
linked from the registry- Mattes MD, Eubank TD, Almubarak M, Wen S, Marano GD, Jacobson GM, Ma PC. A Prospective Trial Evaluating the Safety and Systemic Response From the Concurrent Use of Radiation Therapy with Checkpoint Inhibitor Immunotherapy in Metastatic Non-Small Cell Lung Cancer. Clin Lung Cancer. 2021 Jul;22(4):268-273. doi: 10.1016/j.cllc.2021.01.012. Epub 2021 Jan 25. PubMed 33608212