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Clinical trial · no report yet · Phase 2

NCT03194542

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.

ChannelFound
X threads4
YouTube3

The trial

ClinicalTrials.gov
Official title
A Phase-2 Study To Determine Efficacy and Safety of Luspatercept in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis and Anemia With or Without Red Blood Cell-Transfusion Dependence
Phase
Phase 2
Status
Completed
Conditions
Primary Myelofibrosis; Anemia
Interventions
Luspatercept
Arms
  • Luspatercept in subjects with MPN-associated myelofibrosis · Experimental
Enrollment
95
Primary outcomes
  • The Number of Participants With Anemia Responses Over Any 84-Day Period During the Primary Treatment Period
Sponsor
Celgene
Start
Nov 15, 2017
Primary completion
Jul 18, 2022
Results posted
Yes
Registry record
NCT03194542 · updated Aug 24, 2023

Publications

linked from the registry
  • Gerds AT, Harrison C, Kiladjian JJ, Mesa R, Vannucchi AM, Komrokji R, Bose P, Kremyanskaya M, Mead AJ, Gotlib J, Rose S, Sanabria F, Marsousi N, Giuseppi AC, Jiang H, Palmer JM, McCaul K, Ribrag V, Passamonti F. Safety and efficacy of luspatercept for the treatment of anemia in patients with myelofibrosis. Blood Adv. 2024 Sep 10;8(17):4511-4522. doi: 10.1182/bloodadvances.2024012939. PubMed 38820422