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Clinical trial · no report yet · Phase 2

NCT03639935

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
Phase II Multi-Center Study of PARP Inhibitor Rucaparib in Combination With Anti-PD-1 Antibody Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy
Phase
Phase 2
Status
Completed
Conditions
Biliary Tract Cancer
Interventions
Rucaparib; Nivolumab
Arms
  • Rucaparib and Nivolumab · Experimental
Enrollment
32
Primary outcomes
  • Proportion of Patients Alive and Without Radiological or Clinical Progression at 4 Months
Sponsor
University of Michigan Rogel Cancer Center with Dana-Farber Cancer Institute, Vanderbilt University Medical Center
Start
Mar 28, 2019
Primary completion
Feb 7, 2023
Results posted
Yes
Registry record
NCT03639935 · updated Jun 3, 2025

Publications

linked from the registry
  • Mohan A, Griffith KA, Goff LW, Crysler O, Enzler T, Cardin DB, Gunchick V, Tsang AP, Dippman D, Young AS, Olivei AC, Mannan R, Rao A, Frankel TL, Kumar-Sinha C, Zalupski MM, Sahai V. A phase 2 multicenter trial of rucaparib and nivolumab as maintenance therapy in patients with advanced biliary tract cancer: BilT-02. Clin Cancer Res. 2026 Jul 23. doi: 10.1158/1078-0432.CCR-25-1114. Online ahead of print. PubMed 42489677