Clinical trial · no report yet · Phase 3
NCT04095364
Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
- NCT04095364 ↗
- Active not recruiting
- NRG Oncology
- 13 commentary sources found
- Standard
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.
| Channel | Found | |
|---|---|---|
| YouTube | 6 | |
| Podcasts | 6 | |
| X threads | 1 |
The trial
ClinicalTrials.gov- Official title
- A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients With Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum
- Phase
- Phase 3
- Status
- Active not recruiting
- Conditions
- Low Grade Fallopian Tube Serous Adenocarcinoma; Ovarian Low Grade Serous Adenocarcinoma; Primary Peritoneal Low Grade Serous Adenocarcinoma; Stage II Fallopian Tube Cancer AJCC v8; Stage II Ovarian Cancer AJCC v8; Stage II Primary Peritoneal Cancer AJCC v8; Stage III Fallopian Tube Cancer AJCC v8; Stage III Ovarian Cancer AJCC v8; Stage III Primary Peritoneal Cancer AJCC v8; Stage IV Fallopian Tube Cancer AJCC v8; Stage IV Ovarian Cancer AJCC v8; Stage IV Primary Peritoneal Cancer AJCC v8
- Interventions
- Biopsy Procedure; Biospecimen Collection; Carboplatin; Imaging Procedure; Letrozole; Paclitaxel
- Arms
- Arm I (paclitaxel, carboplatin, letrozole) · Experimental
- Arm II (letrozole) · Experimental
- Enrollment
- 450 (estimated)
- Primary outcomes
- Progression-free survival (PFS)
- Sponsor
- NRG Oncology with National Cancer Institute (NCI)
- Start
- Sep 20, 2019
- Primary completion
- Feb 1, 2027 (estimated)
- Results posted
- No
- Registry record
- NCT04095364 · updated Mar 24, 2026
Publications
linked from the registry- Ilenkovan N, Ryan N, Roxburgh P, Bell S, Gourley C. Controversies in the management of serous borderline tumors and low-grade serous ovarian cancer. Int J Gynecol Cancer. 2025 Mar;35(3):101673. doi: 10.1016/j.ijgc.2025.101673. Epub 2025 Jan 30. PubMed 40058134