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Clinical trial · no report yet · Phase 3

NCT04155034

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

  • NCT04155034 ↗
  • Active not recruiting
  • SWOG Cancer Research Network
  • 32 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads23
Podcasts5
YouTube4

The trial

ClinicalTrials.gov
Official title
MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)
Phase
Phase 3
Status
Active not recruiting
Conditions
Extensive Stage Lung Small Cell Carcinoma; Limited Stage Lung Small Cell Carcinoma; Lung Small Cell Carcinoma
Interventions
Magnetic Resonance Imaging; Prophylactic Cranial Irradiation
Arms
  • Arm I (PCI, MRI) · Active comparator
  • Arm II (MRI) · Experimental
Enrollment
668 (estimated)
Primary outcomes
  • Overall survival (OS)
Sponsor
SWOG Cancer Research Network with National Cancer Institute (NCI)
Start
May 4, 2020
Primary completion
Mar 17, 2026
Results posted
No
Registry record
NCT04155034 · updated Jun 11, 2026

Publications

linked from the registry
  • Schneiders FL, Senan S. New strategies for patients with limited-stage small-cell lung cancer. Lancet Respir Med. 2024 Oct;12(10):748-750. doi: 10.1016/S2213-2600(24)00223-6. Epub 2024 Aug 12. No abstract available. PubMed 39146945