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Clinical trial · no report yet · Phase 3

NCT05197192

A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL

  • NCT05197192 ↗
  • Recruiting
  • German CLL Study Group
  • 27 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube14
Podcasts8
X threads5

The trial

ClinicalTrials.gov
Official title
A Prospective, Open-label, Multicentre, Randomized, Phase-3-trial of Acalabrutinib, Obinutuzumab and Venetoclax (GAVE) Compared to Obinutuzumab and Venetoclax (GVE) in Previously Untreated Patients With High Risk Chronic Lymphocytic Leukemia (CLL)
Phase
Phase 3
Status
Recruiting
Conditions
Chronic Lymphocytic Leukemia
Interventions
Obinutuzumab; Venetoclax; Acalabrutinib
Arms
  • GAVe-Arm · Experimental
  • GVe-Arm · Experimental
Enrollment
202 (estimated)
Primary outcomes
  • Progression-free survival (PFS)
Sponsor
German CLL Study Group with AstraZeneca
Start
Apr 19, 2022
Primary completion
May 2028 (estimated)
Results posted
No
Registry record
NCT05197192 · updated Aug 20, 2026