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Clinical trial · no report yet · Phase 2

NCT05226117

Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads34
YouTube6
Podcasts3

The trial

ClinicalTrials.gov
Official title
SURE-01_An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Sacituzumab Govitecan, Before Radical Cystectomy, for Patients With Muscleinvasive Bladder Cancer Who Cannot Receive or Refuse Cisplatin-based Chemotherapy
Phase
Phase 2
Status
Completed
Conditions
Urothelial Carcinoma
Interventions
Sacituzumab govitecan
Arms
  • Treatment arm · Experimental
Enrollment
44
Primary outcomes
  • Pathological complete response
Sponsor
IRCCS San Raffaele with High Research
Start
Mar 23, 2022
Primary completion
Sep 24, 2025
Results posted
No
Registry record
NCT05226117 · updated Mar 27, 2026

Publications

linked from the registry
  • Necchi A, de Jong JJ, Maiorano BA, Proudfoot JA, Basile G, Cigliola A, Mercinelli C, Tateo V, Piacentini M, Crupi E, Pastorino GL, Latini G, Tomasi E, Davicioni E, Moschini M, Brembilla G, Colecchia M, de Cobelli F, Ross JS, Madison R, Tambaoan CFB, Briganti A, Montorsi F. Neoadjuvant Sacituzumab Govitecan in Patients With Muscle-Invasive Bladder Cancer: Primary Results of the SURE-01 Trial. J Clin Oncol. 2026 Jul 20;44(21):2017-2028. doi: 10.1200/JCO-26-00142. Epub 2026 May 31. PubMed 42218654