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Clinical trial · no report yet · Phase 2

NCT05361720

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

  • NCT05361720 ↗
  • Recruiting
  • Vanderbilt-Ingram Cancer Center
  • 29 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads18
YouTube7
Podcasts4

The trial

ClinicalTrials.gov
Official title
Optimal Treatment by Invoking Biologic Clusters in Renal Cell Carcinoma (OPTIC RCC)
Phase
Phase 2
Status
Recruiting
Conditions
Advanced Clear Cell Renal Cell Carcinoma; Metastatic Clear Cell Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8
Interventions
Cabozantinib; Ipilimumab; Nivolumab
Arms
  • Arm I (ipilimumab, nivolumab) · Experimental
  • Arm II (nivolumab, cabozantinib) · Experimental
Enrollment
54 (estimated)
Primary outcomes
  • Overall response rate (ORR) (Arm 1)
  • Overall response rate (Arm 2)
Sponsor
Vanderbilt-Ingram Cancer Center with National Cancer Institute (NCI), United States Department of Defense
Start
Dec 6, 2022
Primary completion
Oct 1, 2027 (estimated)
Results posted
No
Registry record
NCT05361720 · updated Aug 19, 2026