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Clinical trial · no report yet · Phase 3

NCT05863195

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

  • NCT05863195 ↗
  • Recruiting
  • ECOG-ACRIN Cancer Research Group
  • 38 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads33
Podcasts4
YouTube1

The trial

ClinicalTrials.gov
Official title
A Randomized Phase III Study of Systemic Therapy With or Without Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases: The PUMP Trial
Phase
Phase 3
Status
Recruiting
Conditions
Metastatic Colorectal Carcinoma; Metastatic Malignant Neoplasm in the Liver; Stage IV Colorectal Cancer AJCC v8; Unresectable Colorectal Carcinoma
Interventions
Bevacizumab; Capecitabine; Cetuximab; Computed Tomography; Floxuridine; Fluorouracil; Implantation; Intrahepatic Infusion Procedure; Irinotecan; Leucovorin; Magnetic Resonance Imaging; Oxaliplatin; Panitumumab; Single Photon Emission Computed Tomography
Arms
  • Arm A (HAI, floxuridine, standard chemotherapy) · Experimental
  • Arm B (standard chemotherapy) · Active comparator
Enrollment
408 (estimated)
Primary outcomes
  • Overall survival (OS)
Sponsor
ECOG-ACRIN Cancer Research Group
Start
Apr 10, 2024
Primary completion
Jun 30, 2029 (estimated)
Results posted
No
Registry record
NCT05863195 · updated Sep 24, 2026